SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dvj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BDW_B_DVAB8_0 (GRAMICIDIN A)	2dvj	V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ISOFORM A (Homo sapiens)	3 / 3	VAL A 37 VAL A 51 TRP A 15	None	0.84A	1bdwA-2dvjA: undetectable 1bdwB-2dvjA: undetectable	1bdwA-2dvjA: 7.61 1bdwB-2dvjA: 7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z53_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A E-SITE DNA)	2dvj	V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ISOFORM A (Homo sapiens)	4 / 7	GLY A 126 GLY A 124 GLU A 149 SER A 52	None	0.92A	4z53A-2dvjA: undetectable 4z53B-2dvjA: undetectable	4z53A-2dvjA: 16.79 4z53B-2dvjA: 16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_B_SAMB601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	2dvj	V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ISOFORM A (Homo sapiens)	5 / 12	LEU A 151 ILE A 161 VAL A 184 VAL A 187 VAL A 137	None	1.02A	5dpdB-2dvjA: undetectable	5dpdB-2dvjA: 18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YN6_A_SAMA401_0 (NSP16 PROTEIN)	2dvj	V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ISOFORM A (Homo sapiens)	5 / 12	GLY A 145 ASN A 144 ASP A 142 ASP A 150 PHE A 153	None	1.35A	5yn6A-2dvjA: undetectable	5yn6A-2dvjA: 20.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BDW_B_DVAB8_0","GRAMICIDIN A","2dvj","V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ISOFORM A","Homo sapiens",3,"VAL A  37;VAL A  51;TRP A  15","None","0.84A","1bdwA-2dvjA:undetectable;1bdwB-2dvjA:undetectable","1bdwA-2dvjA:7.61;1bdwB-2dvjA:7.61"],["4Z53_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;E-SITE DNA","2dvj","V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ISOFORM A","Homo sapiens",4,"GLY A 126;GLY A 124;GLU A 149;SER A  52","None","0.92A","4z53A-2dvjA:undetectable;4z53B-2dvjA:undetectable","4z53A-2dvjA:16.79;4z53B-2dvjA:16.79"],["5DPD_B_SAMB601_0","PROTEIN LYSINE METHYLTRANSFERASE 1","2dvj","V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ISOFORM A","Homo sapiens",5,"LEU A 151;ILE A 161;VAL A 184;VAL A 187;VAL A 137","None","1.02A","5dpdB-2dvjA:undetectable","5dpdB-2dvjA:18.45"],["5YN6_A_SAMA401_0","NSP16 PROTEIN","2dvj","V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ISOFORM A","Homo sapiens",5,"GLY A 145;ASN A 144;ASP A 142;ASP A 150;PHE A 153","None","1.35A","5yn6A-2dvjA:undetectable","5yn6A-2dvjA:20.13"]]