SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dvr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 6 TYR A  89
LEU A  44
VAL A  37
ASP A  94
 None
 1.18A 1dz4A-2dvrA:
undetectable		 1dz4A-2dvrA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 6 TYR A  89
LEU A  44
VAL A  37
ASP A  94
 None
 1.13A 1dz4B-2dvrA:
undetectable		 1dz4B-2dvrA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 6 TYR A  89
LEU A  44
VAL A  37
ASP A  94
 None
 1.16A 2zawA-2dvrA:
undetectable		 2zawA-2dvrA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 6 TYR A  89
LEU A  44
VAL A  37
ASP A  94
 None
 1.13A 3fwgA-2dvrA:
undetectable		 3fwgA-2dvrA:
14.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		7 / 7 TRP A  31
PRO A  32
LEU A  42
LEU A  44
ASN A  90
ILE A  96
MET A  99
 None
 0.33A 3u5jA-2dvrA:
20.5		 3u5jA-2dvrA:
70.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		8 / 8 TRP A  31
PRO A  32
VAL A  37
LEU A  42
LEU A  44
ASN A  90
ILE A  96
MET A  99
 None
 0.39A 3u5kA-2dvrA:
20.8		 3u5kA-2dvrA:
70.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		7 / 7 TRP A  31
PRO A  32
VAL A  37
LEU A  42
LEU A  44
ASN A  90
ILE A  96
 None
 0.39A 3u5kB-2dvrA:
20.6		 3u5kB-2dvrA:
70.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		8 / 8 TRP A  31
PRO A  32
VAL A  37
LEU A  42
LEU A  44
ASN A  90
ILE A  96
MET A  99
 None
 0.40A 3u5kC-2dvrA:
20.1		 3u5kC-2dvrA:
70.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		8 / 8 TRP A  31
PRO A  32
VAL A  37
LEU A  42
LEU A  44
ASN A  90
ILE A  96
MET A  99
 None
 0.59A 3u5kD-2dvrA:
20.8		 3u5kD-2dvrA:
70.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		5 / 5 VAL A  37
LEU A  42
LEU A  44
ASN A  90
ILE A  96
 None
 0.33A 4a9jA-2dvrA:
22.7		 4a9jA-2dvrA:
82.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		5 / 5 VAL A  37
LEU A  42
LEU A  44
ASN A  90
ILE A  96
 None
 0.39A 4a9jB-2dvrA:
23.2		 4a9jB-2dvrA:
82.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		5 / 5 VAL A  37
LEU A  42
LEU A  44
ASN A  90
ILE A  96
 None
 0.41A 4a9jC-2dvrA:
21.2		 4a9jC-2dvrA:
82.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 6 VAL A  37
LEU A  42
TYR A  89
ASN A  90
 None
 0.55A 4a9kA-2dvrA:
17.8		 4a9kA-2dvrA:
34.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		9 / 9 TRP A  31
PRO A  32
GLN A  35
VAL A  37
LEU A  42
LEU A  44
ASN A  90
ILE A  96
MET A  99
 None
 0.42A 4c66A-2dvrA:
20.3		 4c66A-2dvrA:
64.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		7 / 8 TRP A  31
VAL A  37
LEU A  42
LEU A  44
TYR A  89
ASN A  90
ILE A  96
 None
 0.63A 4lzrA-2dvrA:
20.2		 4lzrA-2dvrA:
67.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		6 / 8 TRP A  31
VAL A  37
TYR A  89
ASN A  90
ASP A  94
ILE A  96
 None
 0.64A 4lzrA-2dvrA:
20.2		 4lzrA-2dvrA:
67.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		5 / 8 VAL A  37
LEU A  42
ASN A  90
ASP A  94
ILE A  96
 None
 1.26A 4lzrA-2dvrA:
20.2		 4lzrA-2dvrA:
67.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 7 TYR A  47
MET A  82
ASN A  90
ILE A  96
 None
 0.58A 4y03A-2dvrA:
15.2		 4y03A-2dvrA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		5 / 6 PRO A  32
VAL A  37
TYR A  47
ASN A  90
ILE A  96
 None
 0.97A 5pbeA-2dvrA:
16.4		 5pbeA-2dvrA:
26.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		8 / 8 PRO A  32
VAL A  37
LEU A  42
LEU A  44
CYH A  86
TYR A  89
ASN A  90
ILE A  96
 None
 0.38A 5y1yA-2dvrA:
20.3		 5y1yA-2dvrA:
65.44