SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dw6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 ALA A 294
VAL A 113
TRP A  94
 None
 0.91A 1gmkA-2dw6A:
undetectable
1gmkB-2dw6A:
undetectable		 1gmkA-2dw6A:
4.09
1gmkB-2dw6A:
4.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 ALA A 294
VAL A 113
TRP A  94
 None
 0.83A 1gmkC-2dw6A:
undetectable
1gmkD-2dw6A:
undetectable		 1gmkC-2dw6A:
4.09
1gmkD-2dw6A:
4.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 9 GLY A 352
GLY A 373
ILE A 372
VAL A 148
ILE A 364
 None
 1.06A 1hxwA-2dw6A:
undetectable		 1hxwA-2dw6A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 ILE A 320
TRP A 288
PHE A 236
GLU A 239
 None
None
None
MG  A2001 ( 2.9A)
 1.47A 1nsiA-2dw6A:
undetectable
1nsiB-2dw6A:
undetectable		 1nsiA-2dw6A:
23.04
1nsiB-2dw6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 TRP A 288
PHE A 236
GLU A 239
ILE A 320
 None
None
MG  A2001 ( 2.9A)
None
 1.49A 1nsiA-2dw6A:
undetectable
1nsiB-2dw6A:
undetectable		 1nsiA-2dw6A:
23.04
1nsiB-2dw6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 ILE A 320
TRP A 288
PHE A 236
GLU A 239
 None
None
None
MG  A2001 ( 2.9A)
 1.47A 1nsiC-2dw6A:
undetectable
1nsiD-2dw6A:
undetectable		 1nsiC-2dw6A:
23.04
1nsiD-2dw6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 TRP A 288
PHE A 236
GLU A 239
ILE A 320
 None
None
MG  A2001 ( 2.9A)
None
 1.49A 1nsiC-2dw6A:
undetectable
1nsiD-2dw6A:
undetectable		 1nsiC-2dw6A:
23.04
1nsiD-2dw6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 8 ASN A 266
GLN A 290
ASN A  21
ASP A 213
 None
None
TAR  A1001 (-3.9A)
MG  A2001 ( 2.5A)
 1.35A 1p6kA-2dw6A:
undetectable		 1p6kA-2dw6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 THR A 305
TYR A 302
LEU A 299
GLN A 303
 None
 1.07A 1qzrA-2dw6A:
0.0		 1qzrA-2dw6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 THR A 305
TYR A 302
LEU A 299
GLN A 303
 None
 1.08A 1qzrB-2dw6A:
undetectable		 1qzrB-2dw6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 GLY A 351
GLY A 352
ASP A 122
ASP A 117
GLY A 298
 None
 1.05A 1sqfA-2dw6A:
undetectable		 1sqfA-2dw6A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 VAL A  48
VAL A  34
ASP A 379
 None
 0.78A 2fumD-2dw6A:
undetectable		 2fumD-2dw6A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 ILE A 320
TRP A 288
PHE A 236
GLU A 239
 None
None
None
MG  A2001 ( 2.9A)
 1.46A 2nsiA-2dw6A:
undetectable
2nsiB-2dw6A:
undetectable		 2nsiA-2dw6A:
23.04
2nsiB-2dw6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 TRP A 288
PHE A 236
GLU A 239
ILE A 320
 None
None
MG  A2001 ( 2.9A)
None
 1.46A 2nsiA-2dw6A:
undetectable
2nsiB-2dw6A:
undetectable		 2nsiA-2dw6A:
23.04
2nsiB-2dw6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 ILE A 320
TRP A 288
PHE A 236
GLU A 239
 None
None
None
MG  A2001 ( 2.9A)
 1.45A 2nsiC-2dw6A:
0.1
2nsiD-2dw6A:
undetectable		 2nsiC-2dw6A:
23.04
2nsiD-2dw6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 TRP A 288
PHE A 236
GLU A 239
ILE A 320
 None
None
MG  A2001 ( 2.9A)
None
 1.45A 2nsiC-2dw6A:
0.1
2nsiD-2dw6A:
undetectable		 2nsiC-2dw6A:
23.04
2nsiD-2dw6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 GLY A 259
ARG A 286
TYR A 257
 None
 0.87A 2opxA-2dw6A:
undetectable		 2opxA-2dw6A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 SER A 328
GLU A 341
ASP A 292
 None
TAR  A1001 (-2.8A)
None
 0.84A 2zthA-2dw6A:
undetectable		 2zthA-2dw6A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 LEU A  88
THR A  38
VAL A  48
GLY A  49
ILE A   5
 None
 0.91A 3bf1A-2dw6A:
undetectable
3bf1B-2dw6A:
undetectable		 3bf1A-2dw6A:
21.99
3bf1B-2dw6A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 ILE A 320
TRP A 288
PHE A 236
GLU A 239
 None
None
None
MG  A2001 ( 2.9A)
 1.45A 3e7gA-2dw6A:
0.2
3e7gB-2dw6A:
undetectable		 3e7gA-2dw6A:
23.23
3e7gB-2dw6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 TRP A 288
PHE A 236
GLU A 239
ILE A 320
 None
None
MG  A2001 ( 2.9A)
None
 1.47A 3e7gA-2dw6A:
0.2
3e7gB-2dw6A:
undetectable		 3e7gA-2dw6A:
23.23
3e7gB-2dw6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 ILE A 320
TRP A 288
PHE A 236
GLU A 239
 None
None
None
MG  A2001 ( 2.9A)
 1.45A 3e7gC-2dw6A:
undetectable
3e7gD-2dw6A:
0.1		 3e7gC-2dw6A:
23.23
3e7gD-2dw6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 8 TRP A 288
PHE A 236
GLU A 239
ILE A 320
 None
None
MG  A2001 ( 2.9A)
None
 1.46A 3e7gC-2dw6A:
undetectable
3e7gD-2dw6A:
0.1		 3e7gC-2dw6A:
23.23
3e7gD-2dw6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 8 ASN A 266
GLN A 290
ASN A  21
ASP A 213
 None
None
TAR  A1001 (-3.9A)
MG  A2001 ( 2.5A)
 1.28A 3n62A-2dw6A:
undetectable		 3n62A-2dw6A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 8 ASN A 266
GLN A 290
ASN A  21
ASP A 213
 None
None
TAR  A1001 (-3.9A)
MG  A2001 ( 2.5A)
 1.31A 3n62B-2dw6A:
undetectable		 3n62B-2dw6A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 LEU A  73
VAL A  93
GLY A  49
VAL A  48
ILE A  72
 None
 0.84A 3nu5A-2dw6A:
undetectable		 3nu5A-2dw6A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 10 LEU A  73
VAL A  93
GLY A  49
VAL A  48
ILE A  72
 None
 1.05A 3oxwB-2dw6A:
undetectable		 3oxwB-2dw6A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 10 LEU A  73
VAL A  93
GLY A  49
VAL A  48
ILE A  72
 None
 1.02A 3oxwD-2dw6A:
undetectable		 3oxwD-2dw6A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 LEU A  73
ALA A 119
VAL A  93
MET A  97
GLY A 114
 None
 0.95A 4dc3A-2dw6A:
undetectable		 4dc3A-2dw6A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 8 GLY A  62
LEU A  63
ILE A  64
THR A  12
 None
 0.61A 4em2A-2dw6A:
undetectable		 4em2A-2dw6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 ASN A 266
GLN A 290
ASN A  21
ASP A 213
 None
None
TAR  A1001 (-3.9A)
MG  A2001 ( 2.5A)
 1.27A 4kcnB-2dw6A:
undetectable		 4kcnB-2dw6A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 HIS A 322
TRP A 237
SER A  54
 TAR  A1001 (-3.7A)
None
None
 1.16A 4lrhD-2dw6A:
undetectable		 4lrhD-2dw6A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 5 LEU A 289
SER A 315
LEU A 306
LEU A 277
 None
 1.30A 4n09D-2dw6A:
undetectable		 4n09D-2dw6A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 TRP A 288
PHE A 236
GLU A 239
ILE A 320
 None
None
MG  A2001 ( 2.9A)
None
 1.49A 4nosA-2dw6A:
0.1
4nosB-2dw6A:
undetectable		 4nosA-2dw6A:
23.23
4nosB-2dw6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 7 ILE A 320
TRP A 288
PHE A 236
GLU A 239
 None
None
None
MG  A2001 ( 2.9A)
 1.47A 4nosC-2dw6A:
undetectable
4nosD-2dw6A:
undetectable		 4nosC-2dw6A:
23.23
4nosD-2dw6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 TRP A 288
PHE A 236
GLU A 239
ILE A 320
 None
None
MG  A2001 ( 2.9A)
None
 1.48A 4nosC-2dw6A:
undetectable
4nosD-2dw6A:
undetectable		 4nosC-2dw6A:
23.23
4nosD-2dw6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 ASN A 330
MET A 384
ILE A 364
VAL A 357
 None
 1.01A 4olmA-2dw6A:
undetectable		 4olmA-2dw6A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 MET A 165
MET A 183
TYR A 158
 None
 0.98A 4p6xI-2dw6A:
undetectable		 4p6xI-2dw6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 GLY A 336
PRO A 316
LEU A 306
ASN A 145
LEU A 136
 None
 1.28A 4x61A-2dw6A:
3.8		 4x61A-2dw6A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 5 GLY A 172
ARG A 171
GLY A 168
GLU A 203
 None
 1.22A 4z2eB-2dw6A:
undetectable
4z2eC-2dw6A:
undetectable		 4z2eB-2dw6A:
21.88
4z2eC-2dw6A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 ARG A  65
THR A  12
GLU A  10
ARG A  71
 None
 1.08A 5btaA-2dw6A:
undetectable
5btaB-2dw6A:
undetectable
5btaC-2dw6A:
undetectable		 5btaA-2dw6A:
22.36
5btaB-2dw6A:
20.20
5btaC-2dw6A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 ARG A  71
ARG A  65
THR A  12
GLU A  10
 None
 1.05A 5btcA-2dw6A:
undetectable
5btcC-2dw6A:
undetectable
5btcD-2dw6A:
undetectable		 5btcA-2dw6A:
22.36
5btcC-2dw6A:
22.36
5btcD-2dw6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 ARG A  65
THR A  12
GLU A  10
ARG A  71
 None
 1.10A 5btcA-2dw6A:
undetectable
5btcB-2dw6A:
undetectable
5btcC-2dw6A:
undetectable		 5btcA-2dw6A:
22.36
5btcB-2dw6A:
20.20
5btcC-2dw6A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 GLY A 336
PRO A 316
LEU A 306
ASN A 145
LEU A 136
 None
 1.30A 5emlA-2dw6A:
2.9		 5emlA-2dw6A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 GLY A 336
PRO A 316
LEU A 306
MET A 327
LEU A 136
 None
 1.41A 5emlA-2dw6A:
2.9		 5emlA-2dw6A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 ALA A 125
LEU A 132
ILE A  15
TYR A 350
GLY A  59
 None
 1.20A 5eshA-2dw6A:
undetectable		 5eshA-2dw6A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		5 / 12 ILE A 320
GLY A 339
TYR A 151
ALA A 153
TYR A 302
 None
None
None
TAR  A1001 ( 4.5A)
None
 1.09A 5igvA-2dw6A:
undetectable		 5igvA-2dw6A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		3 / 3 LYS A  78
ASP A  76
ARG A   4
 None
 0.74A 5jwaA-2dw6A:
undetectable
5jwaH-2dw6A:
undetectable		 5jwaA-2dw6A:
20.30
5jwaH-2dw6A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 6 ALA A 388
GLY A  51
THR A 115
ILE A  64
 None
 0.86A 6f8cA-2dw6A:
undetectable		 6f8cA-2dw6A:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 2dw6 BLL6730 PROTEIN
(Bradyrhizobium
japonicum) 		4 / 5 ASN A 340
GLY A  51
HIS A 325
ASP A 292
 None
 0.99A 6gh9A-2dw6A:
undetectable		 6gh9A-2dw6A:
11.22