SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dxq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		3 / 3 THR A  57
SER A   7
ARG A   9
 None
 0.77A 3phnA-2dxqA:
undetectable		 3phnA-2dxqA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		4 / 5 GLY A  14
ASP A  15
GLU A  21
VAL A  88
 None
 1.17A 4nkvD-2dxqA:
undetectable		 4nkvD-2dxqA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.44A 4qvlV-2dxqA:
undetectable
4qvlb-2dxqA:
undetectable		 4qvlV-2dxqA:
22.03
4qvlb-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.43A 4qvlH-2dxqA:
undetectable
4qvlN-2dxqA:
undetectable		 4qvlH-2dxqA:
22.03
4qvlN-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 4qvmV-2dxqA:
undetectable
4qvmb-2dxqA:
undetectable		 4qvmV-2dxqA:
22.03
4qvmb-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 4qvmH-2dxqA:
undetectable
4qvmN-2dxqA:
undetectable		 4qvmH-2dxqA:
22.03
4qvmN-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 4qvwV-2dxqA:
undetectable
4qvwb-2dxqA:
undetectable		 4qvwV-2dxqA:
22.03
4qvwb-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 4qvwH-2dxqA:
undetectable
4qvwN-2dxqA:
undetectable		 4qvwH-2dxqA:
22.03
4qvwN-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 4qw0V-2dxqA:
undetectable
4qw0b-2dxqA:
undetectable		 4qw0V-2dxqA:
22.03
4qw0b-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 4qw0H-2dxqA:
undetectable
4qw0N-2dxqA:
undetectable		 4qw0H-2dxqA:
22.03
4qw0N-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 4qw3V-2dxqA:
undetectable
4qw3b-2dxqA:
undetectable		 4qw3V-2dxqA:
22.03
4qw3b-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 4qw3H-2dxqA:
undetectable
4qw3N-2dxqA:
undetectable		 4qw3H-2dxqA:
22.03
4qw3N-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 5d0xV-2dxqA:
undetectable
5d0xb-2dxqA:
undetectable		 5d0xV-2dxqA:
22.03
5d0xb-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 11 HIS A 105
THR A  52
THR A  67
GLY A  12
ALA A  10
 None
 1.42A 5d0xH-2dxqA:
undetectable
5d0xN-2dxqA:
undetectable		 5d0xH-2dxqA:
22.03
5d0xN-2dxqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  60
LEU A  19
LEU A  20
GLU A  21
LEU A  22
 None
 0.95A 5nwwA-2dxqA:
undetectable		 5nwwA-2dxqA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2dxq ACETYLTRANSFERASE
(Agrobacterium
fabrum) 		4 / 7 GLY A  18
LEU A  33
THR A  35
ALA A  38
 None
 0.55A 5o96C-2dxqA:
undetectable		 5o96C-2dxqA:
21.29