SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dyc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2dyc GALECTIN-4
(Mus
musculus) 		3 / 3 VAL A  60
ALA A  61
HIS A 126
 None
 0.68A 1q23H-2dycA:
undetectable		 1q23H-2dycA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2dyc GALECTIN-4
(Mus
musculus) 		3 / 3 VAL A  60
ALA A  61
HIS A 126
 None
 0.66A 1q23J-2dycA:
undetectable		 1q23J-2dycA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 2dyc GALECTIN-4
(Mus
musculus) 		4 / 5 PHE A  76
PHE A  46
PHE A 121
ILE A 147
 None
 1.12A 2v0mD-2dycA:
undetectable		 2v0mD-2dycA:
16.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_A_1GNA998_1
(GALECTIN-7)		 2dyc GALECTIN-4
(Mus
musculus) 		6 / 6 HIS A  63
ASN A  65
ARG A  67
ASN A  77
TRP A  84
GLU A  87
 None
 0.50A 3galA-2dycA:
23.6		 3galA-2dycA:
35.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_B_1GNB999_1
(GALECTIN-7)		 2dyc GALECTIN-4
(Mus
musculus) 		6 / 6 HIS A  63
ASN A  65
ARG A  67
ASN A  77
TRP A  84
GLU A  87
 None
 0.48A 3galB-2dycA:
23.5		 3galB-2dycA:
35.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2dyc GALECTIN-4
(Mus
musculus) 		4 / 8 HIS A  63
ASN A  65
HIS A  47
GLY A 140
 None
 0.94A 5m8rC-2dycA:
undetectable		 5m8rC-2dycA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 2dyc GALECTIN-4
(Mus
musculus) 		6 / 7 HIS A  63
ASN A  65
ARG A  67
ASN A  77
TRP A  84
GLU A  87
 None
 0.40A 6b8kA-2dycA:
23.7		 6b8kA-2dycA:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 2dyc GALECTIN-4
(Mus
musculus) 		6 / 8 HIS A  63
ASN A  65
ARG A  67
ASN A  77
TRP A  84
GLU A  87
 None
 0.61A 6b94A-2dycA:
18.9		 6b94A-2dycA:
26.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 2dyc GALECTIN-4
(Mus
musculus) 		6 / 10 HIS A  63
ASN A  65
ARG A  67
ASN A  77
TRP A  84
GLU A  87
 None
 0.60A 6b94A-2dycA:
18.9
6b94B-2dycA:
18.5		 6b94A-2dycA:
26.12
6b94B-2dycA:
26.12