SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2dyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 7 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.84A 1rxcC-2dyyA:
undetectable
1rxcC-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 7 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.95A 1rxcD-2dyyA:
undetectable
1rxcD-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 8 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.99A 1rxcE-2dyyA:
undetectable
1rxcE-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 7 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
1.00A 1rxcF-2dyyA:
undetectable
1rxcF-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 8 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.97A 1rxcK-2dyyA:
undetectable
1rxcK-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 7 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
1.01A 1rxcL-2dyyA:
undetectable
1rxcL-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 7 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.98A 4e1vB-2dyyA:
undetectable
4e1vB-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 8 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.95A 4e1vC-2dyyA:
undetectable
4e1vC-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 8 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.98A 4e1vD-2dyyA:
undetectable
4e1vD-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 8 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.97A 4e1vE-2dyyA:
undetectable
4e1vE-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 8 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.94A 4e1vG-2dyyA:
undetectable
4e1vG-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
4 / 8 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
0.96A 4e1vH-2dyyA:
undetectable
4e1vH-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)
2dyy UPF0076 PROTEIN
PH0854

(Pyrococcus
horikoshii)
5 / 9 VAL A  75
GLU A 118
VAL A  54
ILE A  58
ALA A 123
None
1.13A 4fwdA-2dyyA:
undetectable
4fwdA-2dyyA:
10.61