SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2e0q THIOREDOXIN
(Sulfurisphaera
tokodaii) 		5 / 10 SER A  47
ASN A  44
ILE A  38
GLY A  87
GLY A 115
 None
 1.27A 1mehA-2e0qA:
undetectable		 1mehA-2e0qA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 2e0q THIOREDOXIN
(Sulfurisphaera
tokodaii) 		4 / 5 GLY A  85
HIS A  52
ILE A  54
PHE A 112
 None
 0.95A 1xf1A-2e0qA:
undetectable		 1xf1A-2e0qA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9X_B_ACTB502_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 2e0q THIOREDOXIN
(Sulfurisphaera
tokodaii) 		4 / 4 LYS A 135
GLU A 140
GLN A  83
TYR A  81
 None
 0.79A 3r9xB-2e0qA:
0.0		 3r9xB-2e0qA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 2e0q THIOREDOXIN
(Sulfurisphaera
tokodaii) 		4 / 7 VAL A 109
VAL A  37
PHE A  86
ILE A 134
 None
 0.90A 3zjqA-2e0qA:
undetectable		 3zjqA-2e0qA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 2e0q THIOREDOXIN
(Sulfurisphaera
tokodaii) 		4 / 7 VAL A 109
VAL A  37
PHE A  86
ILE A 134
 None
 0.92A 3zjqB-2e0qA:
undetectable		 3zjqB-2e0qA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2e0q THIOREDOXIN
(Sulfurisphaera
tokodaii) 		3 / 3 LEU A  40
SER A  42
PHE A  45
 None
 0.53A 6fgcA-2e0qA:
undetectable		 6fgcA-2e0qA:
15.65