SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e0t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 2e0t DUAL SPECIFICITY
PHOSPHATASE 26
(Homo
sapiens) 		3 / 3 GLN A  74
TYR A 106
ARG A 112
 None
 0.93A 1gtbA-2e0tA:
undetectable		 1gtbA-2e0tA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 2e0t DUAL SPECIFICITY
PHOSPHATASE 26
(Homo
sapiens) 		4 / 6 ASN A  78
ALA A  77
HIS A 151
ASP A  73
 None
 1.35A 3aruA-2e0tA:
undetectable		 3aruA-2e0tA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 2e0t DUAL SPECIFICITY
PHOSPHATASE 26
(Homo
sapiens) 		4 / 8 LEU A 167
GLU A  64
LEU A 141
ILE A 148
 None
 0.61A 5mzjA-2e0tA:
undetectable		 5mzjA-2e0tA:
18.59