SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e1f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2e1f WERNER SYNDROME
ATP-DEPENDENT
HELICASE
(Homo
sapiens) 		4 / 8 LEU A1184
VAL A1218
LEU A1216
VAL A1198
 None
 0.72A 2bdmA-2e1fA:
undetectable		 2bdmA-2e1fA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 2e1f WERNER SYNDROME
ATP-DEPENDENT
HELICASE
(Homo
sapiens) 		3 / 3 THR A1180
PRO A1192
ARG A1191
 None
 0.82A 5nd7B-2e1fA:
undetectable		 5nd7B-2e1fA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2e1f WERNER SYNDROME
ATP-DEPENDENT
HELICASE
(Homo
sapiens) 		4 / 6 VAL A1204
LEU A1212
LEU A1216
LEU A1160
 None
 0.94A 6f6sA-2e1fA:
undetectable
6f6sB-2e1fA:
undetectable		 6f6sA-2e1fA:
25.89
6f6sB-2e1fA:
18.81