SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UPF_A_URFA999_1 (URACIL PHOSPHORIBOSYLTRANSF ERASE)	2e2d	METALLOPROTEINASE INHIBITOR 2 (Bos taurus)	4 / 5	MET C1096 ALA C1090 ILE C1017 ASP C1102	None	1.01A	1upfA-2e2dC: undetectable	1upfA-2e2dC: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UPF_B_URFB999_1 (URACIL PHOSPHORIBOSYLTRANSF ERASE)	2e2d	METALLOPROTEINASE INHIBITOR 2 (Bos taurus)	5 / 7	MET C1096 ALA C1090 ILE C1017 ILE C1086 ASP C1102	None	1.20A	1upfB-2e2dC: undetectable	1upfB-2e2dC: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UPF_C_URFC999_1 (URACIL PHOSPHORIBOSYLTRANSF ERASE)	2e2d	METALLOPROTEINASE INHIBITOR 2 (Bos taurus)	4 / 5	MET C1096 ALA C1090 ILE C1017 ASP C1102	None	1.06A	1upfC-2e2dC: undetectable	1upfC-2e2dC: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WU8_C_ADNC502_1 (HYPOTHETICAL PROTEIN PH0463)	2e2d	METALLOPROTEINASE INHIBITOR 2 (Bos taurus)	4 / 7	PHE C1062 ASN C1095 TYR C1064 VAL C1029	None	1.09A	1wu8A-2e2dC: undetectable 1wu8C-2e2dC: undetectable	1wu8A-2e2dC: 18.39 1wu8C-2e2dC: 18.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UPF_A_URFA999_1","URACIL PHOSPHORIBOSYLTRANSFERASE","2e2d","METALLOPROTEINASE INHIBITOR 2","Bos taurus",4,"MET C1096;ALA C1090;ILE C1017;ASP C1102","None","1.01A","1upfA-2e2dC:undetectable","1upfA-2e2dC:19.47"],["1UPF_B_URFB999_1","URACIL PHOSPHORIBOSYLTRANSFERASE","2e2d","METALLOPROTEINASE INHIBITOR 2","Bos taurus",5,"MET C1096;ALA C1090;ILE C1017;ILE C1086;ASP C1102","None","1.20A","1upfB-2e2dC:undetectable","1upfB-2e2dC:19.47"],["1UPF_C_URFC999_1","URACIL PHOSPHORIBOSYLTRANSFERASE","2e2d","METALLOPROTEINASE INHIBITOR 2","Bos taurus",4,"MET C1096;ALA C1090;ILE C1017;ASP C1102","None","1.06A","1upfC-2e2dC:undetectable","1upfC-2e2dC:19.47"],["1WU8_C_ADNC502_1","HYPOTHETICAL PROTEIN PH0463;HYPOTHETICAL PROTEIN PH0463","2e2d","METALLOPROTEINASE INHIBITOR 2","Bos taurus",4,"PHE C1062;ASN C1095;TYR C1064;VAL C1029","None","1.09A","1wu8A-2e2dC:undetectable;1wu8C-2e2dC:undetectable","1wu8A-2e2dC:18.39;1wu8C-2e2dC:18.39"]]