SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		4 / 8 ASP A 209
PHE A 270
LEU A 128
TRP A 140
 None
 1.11A 1rmtD-2e32A:
undetectable		 1rmtD-2e32A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		4 / 5 VAL A 245
TYR A 221
VAL A 288
SER A 175
 None
 1.13A 2x45A-2e32A:
undetectable		 2x45A-2e32A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 10 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.19A 3fhjA-2e32A:
undetectable		 3fhjA-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 10 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.19A 3fhjB-2e32A:
undetectable		 3fhjB-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 10 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.20A 3fhjC-2e32A:
undetectable		 3fhjC-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.19A 3fhjD-2e32A:
undetectable		 3fhjD-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 10 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.19A 3fhjE-2e32A:
undetectable		 3fhjE-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.19A 3fhjF-2e32A:
undetectable		 3fhjF-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.17A 3fi0A-2e32A:
undetectable		 3fi0A-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.16A 3fi0C-2e32A:
undetectable		 3fi0C-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.19A 3fi0D-2e32A:
undetectable		 3fi0D-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.18A 3fi0F-2e32A:
undetectable		 3fi0F-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.18A 3fi0H-2e32A:
undetectable		 3fi0H-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 8 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.17A 3fi0I-2e32A:
undetectable		 3fi0I-2e32A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.18A 3fi0J-2e32A:
undetectable		 3fi0J-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.18A 3fi0K-2e32A:
undetectable		 3fi0K-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.18A 3fi0L-2e32A:
undetectable		 3fi0L-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.16A 3fi0M-2e32A:
undetectable		 3fi0M-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.18A 3fi0N-2e32A:
undetectable		 3fi0N-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.19A 3fi0O-2e32A:
undetectable		 3fi0O-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.16A 3fi0R-2e32A:
undetectable		 3fi0R-2e32A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 10 HIS A 256
VAL A 207
PHE A 270
LEU A 223
THR A 240
 None
 1.47A 3zncA-2e32A:
undetectable		 3zncA-2e32A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		3 / 3 HIS A 272
TRP A 179
SER A 291
 None
 1.10A 4lrhD-2e32A:
undetectable		 4lrhD-2e32A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		3 / 3 VAL A 207
VAL A 293
GLN A 184
 None
 0.68A 5qglA-2e32A:
undetectable		 5qglA-2e32A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		3 / 3 VAL A 207
VAL A 293
GLN A 184
 None
 0.71A 5qh1A-2e32A:
undetectable		 5qh1A-2e32A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		3 / 3 VAL A 207
VAL A 293
GLN A 184
 None
 0.70A 5qhcA-2e32A:
undetectable		 5qhcA-2e32A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		3 / 3 VAL A 207
VAL A 293
GLN A 184
 None
 0.69A 5qhgA-2e32A:
undetectable		 5qhgA-2e32A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 2e32 F-BOX ONLY PROTEIN 2
(Mus
musculus) 		4 / 6 ILE A 205
TYR A 261
LEU A 198
VAL A 295
 None
 0.78A 6f6jA-2e32A:
undetectable		 6f6jA-2e32A:
undetectable