SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e3i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_A_BEZA502_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	2e3i	RESTIN (Homo sapiens)	4 / 6	PHE A 118 ASN A 99 ILE A 90 GLY A 116	None	1.08A	1oniA-2e3iA: undetectable 1oniB-2e3iA: undetectable	1oniA-2e3iA: 23.74 1oniB-2e3iA: 23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_D_BEZD508_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	2e3i	RESTIN (Homo sapiens)	4 / 6	PHE A 118 ASN A 99 ILE A 90 GLY A 116	None	1.06A	1oniD-2e3iA: undetectable 1oniF-2e3iA: undetectable	1oniD-2e3iA: 23.74 1oniF-2e3iA: 23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LD6_B_KKKB602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2e3i	RESTIN (Homo sapiens)	5 / 12	PHE A 82 GLY A 78 ALA A 88 THR A 119 ILE A 117	None	1.43A	3ld6B-2e3iA: undetectable	3ld6B-2e3iA: 11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W7B_B_PA1B204_1 (ACYLOXYACYL HYDROLASE SMALL SUBUNIT ACYLOXYACYL HYDROLASE LARGE SUBUNIT)	2e3i	RESTIN (Homo sapiens)	3 / 3	GLY A 116 ASN A 99 ARG A 107	None	0.74A	5w7bD-2e3iA: undetectable	5w7bD-2e3iA: 20.62

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ONI_A_BEZA502_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","2e3i","RESTIN","Homo sapiens",4,"PHE A 118;ASN A  99;ILE A  90;GLY A 116","None","1.08A","1oniA-2e3iA:undetectable;1oniB-2e3iA:undetectable","1oniA-2e3iA:23.74;1oniB-2e3iA:23.74"],["1ONI_D_BEZD508_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","2e3i","RESTIN","Homo sapiens",4,"PHE A 118;ASN A  99;ILE A  90;GLY A 116","None","1.06A","1oniD-2e3iA:undetectable;1oniF-2e3iA:undetectable","1oniD-2e3iA:23.74;1oniF-2e3iA:23.74"],["3LD6_B_KKKB602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2e3i","RESTIN","Homo sapiens",5,"PHE A  82;GLY A  78;ALA A  88;THR A 119;ILE A 117","None","1.43A","3ld6B-2e3iA:undetectable","3ld6B-2e3iA:11.06"],["5W7B_B_PA1B204_1","ACYLOXYACYL HYDROLASE SMALL SUBUNIT;ACYLOXYACYL HYDROLASE LARGE SUBUNIT","2e3i","RESTIN","Homo sapiens",3,"GLY A 116;ASN A  99;ARG A 107","None","0.74A","5w7bD-2e3iA:undetectable","5w7bD-2e3iA:20.62"]]