SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e3l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2e3l TRANSCRIPTION FACTOR
GTF2IRD2 BETA
(Homo
sapiens) 		4 / 8 GLN A  41
MET A  37
LEU A  38
VAL A  46
 None
 0.94A 2bdmA-2e3lA:
undetectable		 2bdmA-2e3lA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 2e3l TRANSCRIPTION FACTOR
GTF2IRD2 BETA
(Homo
sapiens) 		4 / 5 LEU A  85
PHE A  84
PRO A  83
ALA A  43
 None
 1.35A 3vm4A-2e3lA:
undetectable		 3vm4A-2e3lA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 2e3l TRANSCRIPTION FACTOR
GTF2IRD2 BETA
(Homo
sapiens) 		4 / 8 PHE A  16
LEU A  66
HIS A  57
TYR A  34
 None
 1.12A 4f5zA-2e3lA:
undetectable		 4f5zA-2e3lA:
15.59