SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXK_A_IMNA2001_1 (SERUM ALBUMIN)	2e3v	NEURAL CELL ADHESION MOLECULE 1, 140 KDA ISOFORM (Homo sapiens)	4 / 8	SER A 101 PHE A 103 ALA A 25 LEU A 76	None	0.84A	2bxkA-2e3vA: undetectable	2bxkA-2e3vA: 10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXM_A_IMNA2001_1 (SERUM ALBUMIN)	2e3v	NEURAL CELL ADHESION MOLECULE 1, 140 KDA ISOFORM (Homo sapiens)	4 / 8	SER A 101 PHE A 103 ALA A 25 LEU A 76	None	0.83A	2bxmA-2e3vA: undetectable	2bxmA-2e3vA: 10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_B_PAUB601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	2e3v	NEURAL CELL ADHESION MOLECULE 1, 140 KDA ISOFORM (Homo sapiens)	4 / 7	TYR A 43 GLU A 31 GLY A 9 GLY A 91	None	0.77A	5e26A-2e3vA: undetectable 5e26B-2e3vA: undetectable	5e26A-2e3vA: 13.41 5e26B-2e3vA: 13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_C_PAUC602_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	2e3v	NEURAL CELL ADHESION MOLECULE 1, 140 KDA ISOFORM (Homo sapiens)	4 / 7	GLU A 31 GLY A 9 GLY A 91 TYR A 43	None	0.84A	5e26C-2e3vA: undetectable 5e26D-2e3vA: undetectable	5e26C-2e3vA: 13.41 5e26D-2e3vA: 13.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BXK_A_IMNA2001_1","SERUM ALBUMIN","2e3v","NEURAL CELL ADHESION MOLECULE 1, 140 KDA ISOFORM","Homo sapiens",4,"SER A 101;PHE A 103;ALA A  25;LEU A  76","None","0.84A","2bxkA-2e3vA:undetectable","2bxkA-2e3vA:10.79"],["2BXM_A_IMNA2001_1","SERUM ALBUMIN","2e3v","NEURAL CELL ADHESION MOLECULE 1, 140 KDA ISOFORM","Homo sapiens",4,"SER A 101;PHE A 103;ALA A  25;LEU A  76","None","0.83A","2bxmA-2e3vA:undetectable","2bxmA-2e3vA:10.79"],["5E26_B_PAUB601_0","PANTOTHENATE KINASE 2, MITOCHONDRIAL","2e3v","NEURAL CELL ADHESION MOLECULE 1, 140 KDA ISOFORM","Homo sapiens",4,"TYR A  43;GLU A  31;GLY A   9;GLY A  91","None","0.77A","5e26A-2e3vA:undetectable;5e26B-2e3vA:undetectable","5e26A-2e3vA:13.41;5e26B-2e3vA:13.41"],["5E26_C_PAUC602_0","PANTOTHENATE KINASE 2, MITOCHONDRIAL","2e3v","NEURAL CELL ADHESION MOLECULE 1, 140 KDA ISOFORM","Homo sapiens",4,"GLU A  31;GLY A   9;GLY A  91;TYR A  43","None","0.84A","5e26C-2e3vA:undetectable;5e26D-2e3vA:undetectable","5e26C-2e3vA:13.41;5e26D-2e3vA:13.41"]]