SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e4p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2I_D_QPSD1060_1 (ALPHA-1,4-GLUCAN LYASE ISOZYME 1)	2e4p	BIPHENYL DIOXYGENASE FERREDOXIN SUBUNIT (Pseudomonas sp.)	5 / 10	VAL A 12 PHE A 30 SER A 51 SER A 49 VAL A 27	None	1.39A	2x2iD-2e4pA: undetectable	2x2iD-2e4pA: 7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M48_A_21BA704_1 (TRANSPORTER)	2e4p	BIPHENYL DIOXYGENASE FERREDOXIN SUBUNIT (Pseudomonas sp.)	4 / 8	VAL A 100 ASP A 101 TYR A 89 ALA A 6	None	0.78A	4m48A-2e4pA: undetectable	4m48A-2e4pA: 14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZPH_A_PRLA501_0 (ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1)	2e4p	BIPHENYL DIOXYGENASE FERREDOXIN SUBUNIT (Pseudomonas sp.)	4 / 7	VAL A 61 LEU A 50 SER A 49 GLU A 52	None	1.09A	4zphA-2e4pA: undetectable 4zphB-2e4pA: undetectable	4zphA-2e4pA: 14.84 4zphB-2e4pA: 15.83