SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e5h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2e5h	ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 (Homo sapiens)	4 / 5	LEU A 21 PHE A 19 LEU A 26 PHE A 30	None	1.25A	5iy5P-2e5hA: undetectable 5iy5W-2e5hA: undetectable	5iy5P-2e5hA: 14.45 5iy5W-2e5hA: 20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_C_CHDC308_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	2e5h	ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 (Homo sapiens)	4 / 5	LEU A 21 PHE A 19 LEU A 26 PHE A 30	None	1.26A	5xdxC-2e5hA: undetectable 5xdxJ-2e5hA: undetectable	5xdxC-2e5hA: 14.64 5xdxJ-2e5hA: 20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	2e5h	ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 (Homo sapiens)	4 / 5	LEU A 21 PHE A 19 LEU A 26 PHE A 30	None	1.26A	5xdxP-2e5hA: undetectable 5xdxW-2e5hA: undetectable	5xdxP-2e5hA: 14.64 5xdxW-2e5hA: 20.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5IY5_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2e5h","ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1","Homo sapiens",4,"LEU A  21;PHE A  19;LEU A  26;PHE A  30","None","1.25A","5iy5P-2e5hA:undetectable;5iy5W-2e5hA:undetectable","5iy5P-2e5hA:14.45;5iy5W-2e5hA:20.41"],["5XDX_C_CHDC308_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART","2e5h","ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1","Homo sapiens",4,"LEU A  21;PHE A  19;LEU A  26;PHE A  30","None","1.26A","5xdxC-2e5hA:undetectable;5xdxJ-2e5hA:undetectable","5xdxC-2e5hA:14.64;5xdxJ-2e5hA:20.21"],["5XDX_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART","2e5h","ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1","Homo sapiens",4,"LEU A  21;PHE A  19;LEU A  26;PHE A  30","None","1.26A","5xdxP-2e5hA:undetectable;5xdxW-2e5hA:undetectable","5xdxP-2e5hA:14.64;5xdxW-2e5hA:20.21"]]