SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNJ_A_225A501_1 (CYTOCHROME P450 2C8)	2e5y	ATP SYNTHASE EPSILON CHAIN (Bacillus sp. PS3)	5 / 10	ILE A 77 VAL A 25 ALA A 50 VAL A 20 VAL A 6	None	0.90A	2nnjA-2e5yA: undetectable	2nnjA-2e5yA: 14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNJ_A_225A501_1 (CYTOCHROME P450 2C8)	2e5y	ATP SYNTHASE EPSILON CHAIN (Bacillus sp. PS3)	5 / 10	ILE A 77 VAL A 25 VAL A 20 VAL A 6 ILE A 4	None	0.98A	2nnjA-2e5yA: undetectable	2nnjA-2e5yA: 14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKP_B_478B200_1 (PROTEASE)	2e5y	ATP SYNTHASE EPSILON CHAIN (Bacillus sp. PS3)	5 / 8	ALA A 50 VAL A 8 GLY A 65 ILE A 47 ILE A 61	None	1.18A	3ekpA-2e5yA: undetectable	3ekpA-2e5yA: 19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKP_B_478B200_1 (PROTEASE)	2e5y	ATP SYNTHASE EPSILON CHAIN (Bacillus sp. PS3)	5 / 8	LEU A 68 GLY A 65 ALA A 79 VAL A 8 ILE A 77	None	1.24A	3ekpA-2e5yA: undetectable	3ekpA-2e5yA: 19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_F_SAMF401_1 (METHYLTRANSFERASE NSUN4)	2e5y	ATP SYNTHASE EPSILON CHAIN (Bacillus sp. PS3)	3 / 3	ASP A 73 ARG A 71 ASP A 19	None	0.88A	4fp9F-2e5yA: undetectable	4fp9F-2e5yA: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDT_A_ACTA409_0 (FAD:PROTEIN FMN TRANSFERASE)	2e5y	ATP SYNTHASE EPSILON CHAIN (Bacillus sp. PS3)	4 / 5	ILE A 34 VAL A 75 ILE A 77 VAL A 23	None	0.46A	4xdtA-2e5yA: undetectable	4xdtA-2e5yA: 18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OSP_A_ACTA403_0 (CASEIN KINASE II SUBUNIT ALPHA)	2e5y	ATP SYNTHASE EPSILON CHAIN (Bacillus sp. PS3)	4 / 7	VAL A 63 ILE A 61 VAL A 25 ALA A 50	None	0.71A	5ospA-2e5yA: undetectable	5ospA-2e5yA: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OSR_A_ACTA402_0 (CASEIN KINASE II SUBUNIT ALPHA)	2e5y	ATP SYNTHASE EPSILON CHAIN (Bacillus sp. PS3)	4 / 7	VAL A 63 ILE A 61 VAL A 25 ALA A 50	None	0.71A	5osrA-2e5yA: undetectable	5osrA-2e5yA: 18.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2NNJ_A_225A501_1","CYTOCHROME P450 2C8","2e5y","ATP SYNTHASE EPSILON CHAIN","Bacillus sp. PS3",5,"ILE A  77;VAL A  25;ALA A  50;VAL A  20;VAL A   6","None","0.90A","2nnjA-2e5yA:undetectable","2nnjA-2e5yA:14.41"],["2NNJ_A_225A501_1","CYTOCHROME P450 2C8","2e5y","ATP SYNTHASE EPSILON CHAIN","Bacillus sp. PS3",5,"ILE A  77;VAL A  25;VAL A  20;VAL A   6;ILE A   4","None","0.98A","2nnjA-2e5yA:undetectable","2nnjA-2e5yA:14.41"],["3EKP_B_478B200_1","PROTEASE;PROTEASE","2e5y","ATP SYNTHASE EPSILON CHAIN","Bacillus sp. PS3",5,"ALA A  50;VAL A   8;GLY A  65;ILE A  47;ILE A  61","None","1.18A","3ekpA-2e5yA:undetectable","3ekpA-2e5yA:19.84"],["3EKP_B_478B200_1","PROTEASE;PROTEASE","2e5y","ATP SYNTHASE EPSILON CHAIN","Bacillus sp. PS3",5,"LEU A  68;GLY A  65;ALA A  79;VAL A   8;ILE A  77","None","1.24A","3ekpA-2e5yA:undetectable","3ekpA-2e5yA:19.84"],["4FP9_F_SAMF401_1","METHYLTRANSFERASE NSUN4","2e5y","ATP SYNTHASE EPSILON CHAIN","Bacillus sp. PS3",3,"ASP A  73;ARG A  71;ASP A  19","None","0.88A","4fp9F-2e5yA:undetectable","4fp9F-2e5yA:16.48"],["4XDT_A_ACTA409_0","FAD:PROTEIN FMN TRANSFERASE","2e5y","ATP SYNTHASE EPSILON CHAIN","Bacillus sp. PS3",4,"ILE A  34;VAL A  75;ILE A  77;VAL A  23","None","0.46A","4xdtA-2e5yA:undetectable","4xdtA-2e5yA:18.08"],["5OSP_A_ACTA403_0","CASEIN KINASE II SUBUNIT ALPHA","2e5y","ATP SYNTHASE EPSILON CHAIN","Bacillus sp. PS3",4,"VAL A  63;ILE A  61;VAL A  25;ALA A  50","None","0.71A","5ospA-2e5yA:undetectable","5ospA-2e5yA:18.60"],["5OSR_A_ACTA402_0","CASEIN KINASE II SUBUNIT ALPHA","2e5y","ATP SYNTHASE EPSILON CHAIN","Bacillus sp. PS3",4,"VAL A  63;ILE A  61;VAL A  25;ALA A  50","None","0.71A","5osrA-2e5yA:undetectable","5osrA-2e5yA:18.60"]]