SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e66'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2e66 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Pyrococcus
horikoshii) 		5 / 12 ILE A  54
ASN A  31
ALA A  30
LEU A  61
GLU A  59
 None
 1.09A 3ckkA-2e66A:
undetectable		 3ckkA-2e66A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2e66 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Pyrococcus
horikoshii) 		4 / 8 HIS A  73
PRO A  74
ALA A  53
SER A  13
 None
 0.87A 4k0bB-2e66A:
undetectable		 4k0bB-2e66A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2e66 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Pyrococcus
horikoshii) 		4 / 8 HIS A  73
PRO A  74
ALA A  53
SER A  13
 None
 0.86A 4l7iB-2e66A:
undetectable		 4l7iB-2e66A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2e66 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Pyrococcus
horikoshii) 		3 / 3 LEU A  72
PHE A   8
ILE A  69
 None
 0.54A 5dzk1-2e66A:
undetectable
5dzkF-2e66A:
undetectable
5dzkM-2e66A:
undetectable		 5dzk1-2e66A:
9.09
5dzkF-2e66A:
17.21
5dzkM-2e66A:
21.54