SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2e7v	TRANSMEMBRANE PROTEASE (Mus musculus)	4 / 7	ARG A 121 ARG A 89 ILE A 84 PHE A 88	None	1.05A	3ln1C-2e7vA: undetectable	3ln1C-2e7vA: 12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_D_CELD682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2e7v	TRANSMEMBRANE PROTEASE (Mus musculus)	4 / 5	ARG A 121 ARG A 89 ILE A 84 PHE A 88	None	1.07A	3ln1D-2e7vA: undetectable	3ln1D-2e7vA: 12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H1E_A_VDXA501_1 (VITAMIN D3 RECEPTOR)	2e7v	TRANSMEMBRANE PROTEASE (Mus musculus)	5 / 12	LEU A 93 SER A 91 ARG A 141 SER A 137 VAL A 130	None	1.43A	5h1eA-2e7vA: 0.0	5h1eA-2e7vA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNA_A_ACTA307_0 (THIOREDOXIN REDUCTASE)	2e7v	TRANSMEMBRANE PROTEASE (Mus musculus)	3 / 3	ARG A 134 LYS A 127 TYR A 50	None	1.28A	6gnaA-2e7vA: undetectable	6gnaA-2e7vA: 17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNB_A_ACTA307_0 (THIOREDOXIN REDUCTASE)	2e7v	TRANSMEMBRANE PROTEASE (Mus musculus)	3 / 3	ARG A 134 LYS A 127 TYR A 50	None	1.28A	6gnbA-2e7vA: undetectable	6gnbA-2e7vA: 17.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LN1_C_CELC682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2e7v","TRANSMEMBRANE PROTEASE","Mus musculus",4,"ARG A 121;ARG A  89;ILE A  84;PHE A  88","None","1.05A","3ln1C-2e7vA:undetectable","3ln1C-2e7vA:12.10"],["3LN1_D_CELD682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2e7v","TRANSMEMBRANE PROTEASE","Mus musculus",4,"ARG A 121;ARG A  89;ILE A  84;PHE A  88","None","1.07A","3ln1D-2e7vA:undetectable","3ln1D-2e7vA:12.10"],["5H1E_A_VDXA501_1","VITAMIN D3 RECEPTOR","2e7v","TRANSMEMBRANE PROTEASE","Mus musculus",5,"LEU A  93;SER A  91;ARG A 141;SER A 137;VAL A 130","None","1.43A","5h1eA-2e7vA:0.0","5h1eA-2e7vA:19.39"],["6GNA_A_ACTA307_0","THIOREDOXIN REDUCTASE","2e7v","TRANSMEMBRANE PROTEASE","Mus musculus",3,"ARG A 134;LYS A 127;TYR A  50","None","1.28A","6gnaA-2e7vA:undetectable","6gnaA-2e7vA:17.89"],["6GNB_A_ACTA307_0","THIOREDOXIN REDUCTASE","2e7v","TRANSMEMBRANE PROTEASE","Mus musculus",3,"ARG A 134;LYS A 127;TYR A  50","None","1.28A","6gnbA-2e7vA:undetectable","6gnbA-2e7vA:17.89"]]