SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 2e84 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		3 / 3 LEU A 281
PRO A 282
LEU A 410
 None
HEM  A1312 (-3.3A)
None
 0.49A 2qd5B-2e84A:
undetectable		 2qd5B-2e84A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 2e84 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		3 / 3 ARG A 221
HIS A 225
SER A 219
 HEM  A1307 ( 3.2A)
HEM  A1307 ( 3.4A)
None
 0.88A 4mjwA-2e84A:
undetectable
4mjwB-2e84A:
undetectable		 4mjwA-2e84A:
22.62
4mjwB-2e84A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 2e84 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		3 / 3 SER A 219
ARG A 221
HIS A 225
 None
HEM  A1307 ( 3.2A)
HEM  A1307 ( 3.4A)
 0.86A 4mjwA-2e84A:
undetectable
4mjwB-2e84A:
undetectable		 4mjwA-2e84A:
22.62
4mjwB-2e84A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 2e84 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		4 / 4 ALA A 388
VAL A 358
GLY A 380
THR A 379
 HEM  A1311 (-3.9A)
HEM  A1312 ( 4.5A)
None
HEM  A1311 (-4.5A)
 1.11A 4ubeA-2e84A:
undetectable		 4ubeA-2e84A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 2e84 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		4 / 8 VAL A  73
GLY A 120
GLN A 125
THR A 123
 HEM  A1301 (-4.6A)
None
HEM  A1302 (-3.3A)
None
 0.98A 5sxqA-2e84A:
undetectable		 5sxqA-2e84A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 2e84 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		4 / 8 VAL A  73
GLY A 120
GLN A 125
THR A 123
 HEM  A1301 (-4.6A)
None
HEM  A1302 (-3.3A)
None
 1.00A 5sxtA-2e84A:
undetectable		 5sxtA-2e84A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2e84 HIGH-MOLECULAR-WEIGH
T CYTOCHROME C
(Desulfovibrio
vulgaris) 		4 / 8 VAL A  73
GLY A 120
GLN A 125
THR A 123
 HEM  A1301 (-4.6A)
None
HEM  A1302 (-3.3A)
None
 0.97A 5sxtB-2e84A:
undetectable		 5sxtB-2e84A:
22.74