SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2e9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_1
(ORPHAN NUCLEAR
RECEPTOR PXR)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		5 / 12 VAL A 371
MET A 347
SER A 345
HIS A 338
ILE A 306
 None
None
None
CL  A2001 (-4.4A)
None
 1.44A 1skxA-2e9qA:
0.0		 1skxA-2e9qA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		4 / 7 LEU A 137
ARG A  67
THR A  69
LEU A 155
 None
 0.86A 1v55A-2e9qA:
undetectable
1v55J-2e9qA:
undetectable		 1v55A-2e9qA:
19.40
1v55J-2e9qA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		4 / 8 LEU A 137
ARG A  67
THR A  69
LEU A 155
 None
 0.88A 1v55N-2e9qA:
undetectable
1v55W-2e9qA:
undetectable		 1v55N-2e9qA:
19.40
1v55W-2e9qA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		4 / 8 LEU A 137
ARG A  67
THR A  69
LEU A 155
 None
 0.90A 2einA-2e9qA:
undetectable
2einJ-2e9qA:
undetectable		 2einA-2e9qA:
19.40
2einJ-2e9qA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		5 / 11 ALA A  45
ILE A  70
VAL A 245
PHE A 249
LEU A 252
 None
 1.26A 2h42A-2e9qA:
undetectable		 2h42A-2e9qA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		4 / 8 PHE A 394
GLY A 352
GLY A 369
MET A 347
 None
 0.90A 2y6rB-2e9qA:
undetectable		 2y6rB-2e9qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		5 / 12 SER A  81
LEU A 322
PHE A 131
ILE A 100
ALA A  99
 None
 0.88A 3nxuA-2e9qA:
undetectable		 3nxuA-2e9qA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		5 / 12 SER A  81
LEU A 322
PHE A 131
ILE A 100
ALA A  99
 None
 0.94A 3nxuB-2e9qA:
undetectable		 3nxuB-2e9qA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		3 / 3 LYS A 400
GLU A 325
TRP A 396
 None
 1.31A 3v4tH-2e9qA:
undetectable		 3v4tH-2e9qA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		5 / 11 GLN A  91
GLY A  92
ALA A  45
GLY A  46
GLU A  44
 None
 1.20A 4a6nA-2e9qA:
undetectable		 4a6nA-2e9qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		4 / 6 GLY A 226
GLY A 227
GLU A 219
ILE A 224
 None
 0.99A 4fglD-2e9qA:
undetectable		 4fglD-2e9qA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		4 / 6 PHE A 399
MET A  65
ILE A 397
ARG A 326
 None
 1.32A 4mk4B-2e9qA:
undetectable		 4mk4B-2e9qA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		4 / 4 LYS A 287
ASN A 310
ASP A 297
ASP A 135
 None
 1.31A 4o1eB-2e9qA:
undetectable		 4o1eB-2e9qA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2e9q 11S GLOBULIN SUBUNIT
BETA
(Cucurbita
maxima) 		4 / 5 GLY A 291
ASN A 289
ARG A 292
ARG A 132
 None
 1.24A 6dwdB-2e9qA:
undetectable
6dwdD-2e9qA:
undetectable		 6dwdB-2e9qA:
20.70
6dwdD-2e9qA:
20.70