SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eae'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 ASP A 158
ASP A  16
ASP A  17
GLY A 164
PRO A  52
 None
 1.22A 1d4sA-2eaeA:
undetectable		 1d4sA-2eaeA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 ARG A 529
ALA A 517
ALA A 440
GLU A 441
 None
 1.19A 1e7bB-2eaeA:
undetectable		 1e7bB-2eaeA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 5 ARG A 529
ALA A 517
ALA A 440
GLU A 441
 None
 1.17A 1e7cA-2eaeA:
2.2		 1e7cA-2eaeA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 PHE A  53
VAL A  71
ILE A 245
VAL A 307
ASN A 188
 None
 1.24A 1fm4A-2eaeA:
undetectable		 1fm4A-2eaeA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_A_SAMA500_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ASN A 237
PRO A 494
GLY A  92
THR A 457
ASN A 128
 None
 1.16A 1g60A-2eaeA:
undetectable		 1g60A-2eaeA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ASN A 237
PRO A 494
GLY A  92
THR A 457
ASN A 128
 None
 1.18A 1g60B-2eaeA:
undetectable		 1g60B-2eaeA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 PRO A  52
THR A  61
GLY A  59
PHE A 757
GLY A 398
 None
 1.46A 1h4oA-2eaeA:
undetectable
1h4oB-2eaeA:
undetectable		 1h4oA-2eaeA:
11.35
1h4oB-2eaeA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 PRO A  52
THR A  61
GLY A  59
PHE A 757
GLY A 398
 None
 1.44A 1h4oC-2eaeA:
undetectable
1h4oD-2eaeA:
undetectable		 1h4oC-2eaeA:
11.35
1h4oD-2eaeA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 PRO A  52
THR A  61
GLY A  59
PHE A 757
GLY A 398
 None
 1.42A 1h4oE-2eaeA:
undetectable
1h4oF-2eaeA:
undetectable		 1h4oE-2eaeA:
11.35
1h4oF-2eaeA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 ARG A 157
VAL A  71
TRP A  63
 None
 1.16A 1qw6A-2eaeA:
undetectable		 1qw6A-2eaeA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 ARG A 157
VAL A  71
TRP A  63
 None
 1.09A 1qwcA-2eaeA:
undetectable		 1qwcA-2eaeA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 241
THR A 221
TRP A 138
MET A 208
 None
 1.35A 1uw6A-2eaeA:
undetectable
1uw6B-2eaeA:
undetectable		 1uw6A-2eaeA:
12.66
1uw6B-2eaeA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 241
TRP A 138
LEU A 228
MET A 208
 None
 1.42A 1uw6A-2eaeA:
undetectable
1uw6B-2eaeA:
undetectable		 1uw6A-2eaeA:
12.66
1uw6B-2eaeA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 241
THR A 221
TRP A 138
MET A 208
 None
 1.32A 1uw6D-2eaeA:
undetectable
1uw6E-2eaeA:
undetectable		 1uw6D-2eaeA:
12.66
1uw6E-2eaeA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 241
THR A 221
TRP A 138
MET A 208
 None
 1.33A 1uw6G-2eaeA:
undetectable
1uw6H-2eaeA:
undetectable		 1uw6G-2eaeA:
12.66
1uw6H-2eaeA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 241
THR A 221
TRP A 138
MET A 208
 None
 1.31A 1uw6P-2eaeA:
undetectable
1uw6Q-2eaeA:
undetectable		 1uw6P-2eaeA:
12.66
1uw6Q-2eaeA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TRP A 138
MET A 208
TYR A 241
THR A 221
 None
 1.34A 1uw6P-2eaeA:
undetectable
1uw6T-2eaeA:
undetectable		 1uw6P-2eaeA:
12.66
1uw6T-2eaeA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 ARG A 157
VAL A  71
TRP A  63
 None
 1.10A 1vagA-2eaeA:
undetectable		 1vagA-2eaeA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 LEU A 602
HIS A 539
LYS A 535
 None
 1.02A 1y7iA-2eaeA:
undetectable		 1y7iA-2eaeA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 TRP A  18
LEU A 161
LYS A 376
 None
 1.29A 1yajK-2eaeA:
undetectable		 1yajK-2eaeA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 ARG A 157
VAL A  71
TRP A  63
 None
 1.12A 1zviA-2eaeA:
undetectable		 1zviA-2eaeA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 GLY A 126
GLY A 454
ALA A 482
HIS A 483
ALA A 506
 None
 1.05A 2bm9F-2eaeA:
undetectable		 2bm9F-2eaeA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 LEU A 546
THR A 558
GLY A 554
ASP A 555
 None
 0.97A 2ddwB-2eaeA:
undetectable		 2ddwB-2eaeA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 LEU A 682
GLY A 684
LEU A 690
LEU A 685
ILE A 649
 None
 1.10A 2f8dA-2eaeA:
undetectable		 2f8dA-2eaeA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 MET A 752
LEU A 748
LEU A 370
ILE A 728
LEU A 161
 None
 1.14A 2hrcA-2eaeA:
undetectable		 2hrcA-2eaeA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 MET A 752
LEU A 748
LEU A 370
ILE A 728
LEU A 161
 None
 1.17A 2hrcB-2eaeA:
undetectable		 2hrcB-2eaeA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 THR A  72
TYR A 377
PHE A 763
LEU A 159
 None
 1.20A 2hzqA-2eaeA:
undetectable		 2hzqA-2eaeA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 SER A 343
ASP A 158
ASP A  16
 None
 0.67A 2plwA-2eaeA:
undetectable		 2plwA-2eaeA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 10 PRO A  52
THR A  61
GLY A  59
PHE A 757
GLY A 398
 None
 1.41A 2vl2A-2eaeA:
undetectable
2vl2C-2eaeA:
undetectable		 2vl2A-2eaeA:
11.58
2vl2C-2eaeA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 LEU A 353
TYR A 357
GLN A 358
 None
 0.75A 2wekA-2eaeA:
undetectable		 2wekA-2eaeA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ILE A 724
ALA A 732
GLY A 774
GLY A 725
ASN A 799
 None
 1.09A 2y7hB-2eaeA:
undetectable		 2y7hB-2eaeA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 VAL A 867
ARG A 837
ILE A 850
THR A 885
 None
 1.22A 3cl9A-2eaeA:
undetectable		 3cl9A-2eaeA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQZ_A_LQZA586_1
(SERUM ALBUMIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 ASP A 645
LYS A 662
ARG A 556
LYS A 650
 None
 1.21A 3jqzA-2eaeA:
2.2		 3jqzA-2eaeA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 LEU A 373
LEU A 756
THR A 350
LEU A 353
LEU A 748
 None
 1.31A 3ndvA-2eaeA:
undetectable
3ndvB-2eaeA:
undetectable		 3ndvA-2eaeA:
19.27
3ndvB-2eaeA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 THR A 350
LEU A 353
LEU A 748
LEU A 373
LEU A 756
 None
 1.31A 3ndvC-2eaeA:
undetectable
3ndvD-2eaeA:
undetectable		 3ndvC-2eaeA:
19.27
3ndvD-2eaeA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 PHE A 686
ILE A 335
THR A 740
THR A 382
 None
 0.80A 3nxuA-2eaeA:
undetectable		 3nxuA-2eaeA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 GLU A 537
LEU A 511
LEU A 683
 None
 0.78A 3ohtA-2eaeA:
undetectable		 3ohtA-2eaeA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 VAL A 867
VAL A 848
TYR A 891
ILE A 893
 None
 0.93A 3remA-2eaeA:
2.8		 3remA-2eaeA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 THR A 412
ASN A 411
GLY A 405
ASP A 406
LEU A  78
 None
 1.49A 3sfuB-2eaeA:
undetectable		 3sfuB-2eaeA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 HIS A 326
HIS A 322
ILE A 323
 None
 0.58A 3u52A-2eaeA:
undetectable
3u52C-2eaeA:
undetectable		 3u52A-2eaeA:
19.89
3u52C-2eaeA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 LEU A  51
ILE A 765
TYR A 753
TYR A 380
 None
 1.43A 3vt7A-2eaeA:
undetectable		 3vt7A-2eaeA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 THR A 212
ASN A 211
GLY A 139
ASP A 140
 None
 1.34A 3w9tE-2eaeA:
undetectable		 3w9tE-2eaeA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 241
THR A 221
TRP A 138
MET A 208
 None
 1.37A 3wipD-2eaeA:
undetectable
3wipE-2eaeA:
undetectable		 3wipD-2eaeA:
13.04
3wipE-2eaeA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 ASN A 695
SER A 730
LEU A 685
THR A 785
 None
 1.41A 4an2A-2eaeA:
undetectable		 4an2A-2eaeA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 ASN A 755
SER A 162
LEU A 161
THR A  61
 None
 1.42A 4an2A-2eaeA:
undetectable		 4an2A-2eaeA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TRP A 652
HIS A 681
ARG A 709
ILE A 667
 None
 1.28A 4cx7A-2eaeA:
undetectable
4cx7B-2eaeA:
undetectable		 4cx7A-2eaeA:
19.03
4cx7B-2eaeA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 797
ASN A 799
ILE A 850
ALA A 878
 None
 0.81A 4eyzA-2eaeA:
undetectable		 4eyzA-2eaeA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 797
ASN A 799
ILE A 850
ALA A 878
 None
 0.81A 4eyzB-2eaeA:
undetectable		 4eyzB-2eaeA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 ARG A 677
SER A 580
VAL A 422
TRP A 509
 FUL  A 900 (-3.6A)
None
None
None
 1.50A 4klaA-2eaeA:
0.0		 4klaA-2eaeA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 ARG A 733
GLY A 774
ASP A 776
GLY A 770
 None
 1.01A 4koeA-2eaeA:
undetectable
4koeB-2eaeA:
undetectable
4koeC-2eaeA:
undetectable		 4koeA-2eaeA:
19.81
4koeB-2eaeA:
19.81
4koeC-2eaeA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 VAL A 273
ALA A 270
ASP A 226
LEU A 256
 None
 0.80A 4l9iA-2eaeA:
undetectable		 4l9iA-2eaeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 PHE A  73
ILE A 277
PHE A  53
ASN A  55
 None
 1.40A 4o7gA-2eaeA:
1.6
4o7gB-2eaeA:
1.6		 4o7gA-2eaeA:
15.33
4o7gB-2eaeA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 PHE A  73
ILE A 277
PHE A  53
ASN A  55
 None
 1.42A 4o7gB-2eaeA:
1.6		 4o7gB-2eaeA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 LEU A 143
VAL A 267
LEU A 194
TYR A 145
 None
 1.01A 4puoC-2eaeA:
undetectable		 4puoC-2eaeA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 LEU A 143
VAL A 267
LEU A 194
TYR A 145
 None
 1.03A 4pwdC-2eaeA:
undetectable		 4pwdC-2eaeA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 ASN A 119
VAL A 118
GLY A 121
THR A 103
VAL A 561
 None
 1.22A 4r20B-2eaeA:
undetectable		 4r20B-2eaeA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 692
ASN A 695
SER A 696
 None
 0.65A 4tvtA-2eaeA:
undetectable		 4tvtA-2eaeA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 ASN A 108
GLU A 578
TYR A 541
LEU A 546
 None
 1.16A 4twdD-2eaeA:
2.8
4twdE-2eaeA:
3.1		 4twdD-2eaeA:
15.77
4twdE-2eaeA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 ASN A 108
GLU A 578
TYR A 541
LEU A 546
 None
 0.97A 4twdI-2eaeA:
undetectable
4twdJ-2eaeA:
1.3		 4twdI-2eaeA:
15.77
4twdJ-2eaeA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 ASN A 575
SER A 503
ALA A 562
VAL A 561
 None
 0.88A 4x1kC-2eaeA:
undetectable		 4x1kC-2eaeA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 9 ILE A 277
GLY A  60
ILE A  58
ALA A 279
GLU A  75
 None
 1.28A 4yp2B-2eaeA:
undetectable		 4yp2B-2eaeA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 GLY A 774
ASP A 776
GLY A 770
ARG A 733
 None
 0.93A 4z53A-2eaeA:
undetectable
4z53B-2eaeA:
undetectable		 4z53A-2eaeA:
21.85
4z53B-2eaeA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 ARG A 733
GLY A 774
ASP A 776
GLY A 770
 None
 0.94A 4z53A-2eaeA:
undetectable
4z53B-2eaeA:
undetectable		 4z53A-2eaeA:
21.85
4z53B-2eaeA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 SER A 646
ASP A 663
THR A 117
GLU A 116
 None
 0.99A 5btfA-2eaeA:
undetectable
5btfB-2eaeA:
undetectable
5btfC-2eaeA:
undetectable		 5btfA-2eaeA:
20.00
5btfB-2eaeA:
14.67
5btfC-2eaeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 TYR A 380
PHE A 769
TYR A 377
GLY A 398
 None
 0.77A 5esfA-2eaeA:
undetectable		 5esfA-2eaeA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ALA A 321
TYR A 380
PHE A 769
TYR A 377
GLY A 398
 None
 1.22A 5eshA-2eaeA:
undetectable		 5eshA-2eaeA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 ARG A 157
VAL A  71
TRP A  63
 None
 1.08A 5fvoA-2eaeA:
undetectable		 5fvoA-2eaeA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 11 GLN A 764
ASN A 395
VAL A 402
SER A 401
TYR A  38
 FUC  A 899 (-4.3A)
None
None
None
None
 1.37A 5jh7D-2eaeA:
undetectable		 5jh7D-2eaeA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 VAL A 168
HIS A 172
VAL A 152
 None
 0.66A 5jmnC-2eaeA:
undetectable		 5jmnC-2eaeA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 ASN A 575
SER A 503
ALA A 562
VAL A 561
 None
 0.98A 5nm5A-2eaeA:
1.5		 5nm5A-2eaeA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 ALA A 766
GLY A 767
ASN A 750
LEU A 748
GLU A 745
 None
 1.24A 5nwuA-2eaeA:
undetectable		 5nwuA-2eaeA:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 TRP A 722
GLY A 725
ILE A 724
VAL A 422
LEU A 716
 FUL  A 900 ( 3.9A)
None
None
None
None
 1.18A 5nz0A-2eaeA:
1.8		 5nz0A-2eaeA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 GLY A 684
GLY A 688
SER A 696
ALA A 702
 None
 0.77A 5o96C-2eaeA:
undetectable		 5o96C-2eaeA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 7 LEU A 804
GLY A 735
THR A 851
ALA A 852
 None
 0.78A 5o96C-2eaeA:
undetectable		 5o96C-2eaeA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 ASN A 213
ALA A 404
ASP A 406
TYR A 214
 None
 1.18A 5umd2-2eaeA:
undetectable
5umdF-2eaeA:
undetectable		 5umd2-2eaeA:
6.79
5umdF-2eaeA:
6.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 LEU A 107
ALA A 106
LEU A 123
 None
 0.52A 5uunB-2eaeA:
1.7		 5uunB-2eaeA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		5 / 12 THR A 823
VAL A 817
ASN A 435
SER A 327
GLU A 438
 None
 1.49A 5v1tA-2eaeA:
undetectable		 5v1tA-2eaeA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 LEU A 658
THR A 576
ASN A 575
 None
 0.61A 6baaE-2eaeA:
2.5		 6baaE-2eaeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 LEU A 658
THR A 576
ASN A 575
 None
 0.61A 6baaF-2eaeA:
2.5		 6baaF-2eaeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 LEU A 658
THR A 576
ASN A 575
 None
 0.61A 6baaG-2eaeA:
2.4		 6baaG-2eaeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		3 / 3 LEU A 658
THR A 576
ASN A 575
 None
 0.61A 6baaH-2eaeA:
2.5		 6baaH-2eaeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 LEU A 534
TYR A 520
ASP A 689
GLN A 781
 None
None
CA  A 902 (-2.9A)
None
 1.49A 6djzC-2eaeA:
undetectable		 6djzC-2eaeA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 6 LEU A 779
TYR A 520
GLN A 512
GLU A 777
 None
 1.44A 6djzC-2eaeA:
undetectable		 6djzC-2eaeA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 8 SER A 580
TYR A 653
GLY A 656
VAL A 643
 None
 1.05A 6giqL-2eaeA:
undetectable
6giqP-2eaeA:
undetectable
6giqT-2eaeA:
undetectable		 6giqL-2eaeA:
18.58
6giqP-2eaeA:
13.39
6giqT-2eaeA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 HIS A 322
LEU A 159
TYR A 377
GLY A 384
 None
 1.38A 6n91A-2eaeA:
undetectable		 6n91A-2eaeA:
7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 2eae ALPHA-FUCOSIDASE
(Bifidobacterium
bifidum) 		4 / 4 HIS A 322
LEU A 159
TYR A 377
GLY A 384
 None
 1.38A 6n91B-2eaeA:
undetectable		 6n91B-2eaeA:
7.70