SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ebn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		4 / 8 ILE A  91
PHE A 111
ALA A 112
VAL A 168
 None
 0.83A 3me6B-2ebnA:
undetectable		 3me6B-2ebnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		5 / 12 LEU A 273
GLY A 244
PHE A  13
LEU A  12
TYR A 274
 None
 0.83A 3mecA-2ebnA:
undetectable		 3mecA-2ebnA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		5 / 12 LEU A 273
GLY A 244
PHE A  13
LEU A  12
TYR A 274
 None
 0.88A 3medA-2ebnA:
undetectable
3medB-2ebnA:
undetectable		 3medA-2ebnA:
21.09
3medB-2ebnA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		3 / 3 ARG A 255
GLU A  17
THR A  21
 None
 0.89A 3v4tA-2ebnA:
undetectable		 3v4tA-2ebnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		4 / 5 TYR A 229
GLN A 262
GLY A 261
SER A 260
 None
 1.11A 4fu8A-2ebnA:
undetectable		 4fu8A-2ebnA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		3 / 3 MET A 247
ASP A 130
PHE A 129
 None
 0.99A 4xeyA-2ebnA:
undetectable		 4xeyA-2ebnA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		3 / 3 MET A 247
ASP A 130
PHE A 129
 None
 1.00A 4xeyB-2ebnA:
undetectable		 4xeyB-2ebnA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		3 / 3 PHE A 128
ILE A 196
ASP A  40
 None
 0.71A 5cswA-2ebnA:
undetectable		 5cswA-2ebnA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		3 / 3 PHE A 128
ILE A 196
ASP A  40
 None
 0.67A 5cswB-2ebnA:
undetectable		 5cswB-2ebnA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		3 / 3 LYS A  11
LEU A 235
ILE A 248
 None
 0.76A 5kc0A-2ebnA:
undetectable		 5kc0A-2ebnA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_B_6T0B913_0
(TOLL-LIKE RECEPTOR 7)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		5 / 9 VAL A  58
PHE A 111
THR A 159
LEU A 155
ILE A  91
 None
 1.39A 5zsfA-2ebnA:
0.7
5zsfB-2ebnA:
0.0		 5zsfA-2ebnA:
15.02
5zsfB-2ebnA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		4 / 7 ALA A 162
ILE A 100
LEU A 155
ILE A  88
 None
 0.82A 6b5vA-2ebnA:
undetectable
6b5vB-2ebnA:
undetectable		 6b5vA-2ebnA:
14.34
6b5vB-2ebnA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		4 / 6 PHE A 224
VAL A  39
LEU A 278
LEU A 266
 None
 0.98A 6e43A-2ebnA:
undetectable		 6e43A-2ebnA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		4 / 6 PHE A 224
VAL A  39
LEU A 278
LEU A 266
 None
 1.03A 6e43B-2ebnA:
undetectable		 6e43B-2ebnA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Elizabethkingia
meningoseptica) 		4 / 6 PHE A 224
VAL A  39
LEU A 278
LEU A 266
 None
 0.97A 6e43C-2ebnA:
undetectable		 6e43C-2ebnA:
23.17