SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ebu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 2ebu REPLICATION FACTOR C
SUBUNIT 1
(Homo
sapiens) 		4 / 8 TYR A 433
CYH A 406
GLY A 409
TYR A 447
 None
 1.07A 1jlfA-2ebuA:
undetectable
1jlfB-2ebuA:
undetectable		 1jlfA-2ebuA:
12.04
1jlfB-2ebuA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 2ebu REPLICATION FACTOR C
SUBUNIT 1
(Homo
sapiens) 		4 / 7 LEU A 418
GLU A 472
SER A 420
ILE A 421
 None
 1.20A 4tvtA-2ebuA:
undetectable		 4tvtA-2ebuA:
17.87