SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ebz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 2ebz REGULATOR OF
G-PROTEIN SIGNALING
12
(Homo
sapiens) 		3 / 3 THR A  82
GLU A  42
ASP A  34
 None
 0.86A 1nt2A-2ebzA:
undetectable		 1nt2A-2ebzA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 2ebz REGULATOR OF
G-PROTEIN SIGNALING
12
(Homo
sapiens) 		3 / 3 PHE A  47
CYH A  51
PHE A 106
 None
 1.06A 3cr5X-2ebzA:
0.0		 3cr5X-2ebzA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 2ebz REGULATOR OF
G-PROTEIN SIGNALING
12
(Homo
sapiens) 		5 / 12 LEU A  23
LEU A  22
SER A 121
GLN A  49
LEU A  46
 None
 1.15A 3m7rA-2ebzA:
undetectable		 3m7rA-2ebzA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 2ebz REGULATOR OF
G-PROTEIN SIGNALING
12
(Homo
sapiens) 		5 / 12 LEU A  23
GLY A  28
PHE A  19
MET A 117
LEU A  36
 None
 1.27A 5uc3B-2ebzA:
undetectable		 5uc3B-2ebzA:
20.83