SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ece'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 8 LEU A 386
THR A 324
VAL A 323
LEU A 339
ALA A 382
 None
 1.14A 1fiqC-2eceA:
undetectable		 1fiqC-2eceA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 9 LEU A 386
THR A 324
VAL A 323
LEU A 339
ALA A 382
 None
 1.22A 1fo4A-2eceA:
undetectable		 1fo4A-2eceA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 8 ILE A 152
LEU A 169
ILE A 108
GLU A 130
VAL A 131
 None
 1.38A 1linA-2eceA:
undetectable		 1linA-2eceA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		3 / 3 HIS A 141
HIS A  74
HIS A  75
 None
 0.69A 1rkyA-2eceA:
undetectable		 1rkyA-2eceA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 THR A 398
LEU A 449
VAL A 447
VAL A 437
 None
 0.98A 2cppA-2eceA:
undetectable		 2cppA-2eceA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		3 / 3 THR A 113
PRO A 115
PRO A 120
 None
 0.27A 2d55C-2eceA:
undetectable		 2d55C-2eceA:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		3 / 3 PRO A 120
THR A 113
PRO A 115
 None
 0.81A 2d55C-2eceA:
undetectable		 2d55C-2eceA:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 ASN A 407
GLY A  36
THR A  35
SER A 400
 None
 1.05A 2o5yH-2eceA:
undetectable
2o5yL-2eceA:
undetectable		 2o5yH-2eceA:
16.21
2o5yL-2eceA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 4 SER A 138
GLY A 160
HIS A  74
ASP A 406
 None
 1.27A 2oxtC-2eceA:
undetectable		 2oxtC-2eceA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A 164
LEU A 167
ALA A 190
SER A 105
GLY A 102
 None
 0.89A 2vmyB-2eceA:
undetectable		 2vmyB-2eceA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A 164
LEU A 167
ALA A 190
SER A 105
GLY A 102
 None
 0.97A 2vmyA-2eceA:
undetectable		 2vmyA-2eceA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y4N_B_PACB503_0
(PHENYLACETATE-COENZY
ME A LIGASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 4 SER A 105
GLY A 156
GLY A 136
LYS A 132
 None
 1.17A 2y4nB-2eceA:
0.0		 2y4nB-2eceA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 12 TYR A 410
GLY A 343
ALA A 382
ILE A 367
PRO A 301
 None
 1.08A 3jayA-2eceA:
undetectable		 3jayA-2eceA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 10 ILE A  60
ALA A  46
THR A  11
ILE A  99
ILE A 123
 None
 1.18A 3prsA-2eceA:
undetectable		 3prsA-2eceA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		3 / 3 TYR A  29
LEU A 103
ARG A 448
 None
 0.81A 3sufB-2eceA:
undetectable		 3sufB-2eceA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 5 ARG A 370
LEU A 305
PRO A 320
VAL A 319
 None
 1.12A 3ufnA-2eceA:
undetectable
3ufnB-2eceA:
undetectable		 3ufnA-2eceA:
12.10
3ufnB-2eceA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 9 LEU A 386
THR A 324
VAL A 323
LEU A 339
ALA A 382
 None
 1.18A 3unaA-2eceA:
undetectable		 3unaA-2eceA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 9 LEU A 386
THR A 324
VAL A 323
LEU A 339
ALA A 382
 None
 1.18A 3unaB-2eceA:
undetectable		 3unaB-2eceA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 9 LEU A 386
THR A 324
VAL A 323
LEU A 339
ALA A 382
 None
 1.19A 3uncA-2eceA:
0.0		 3uncA-2eceA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 9 LEU A 386
THR A 324
VAL A 323
LEU A 339
ALA A 382
 None
 1.18A 3uncB-2eceA:
0.0		 3uncB-2eceA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 ARG A 346
GLY A 365
ALA A 371
ASP A 372
 None
 0.80A 4eyrB-2eceA:
undetectable		 4eyrB-2eceA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.19A 4feuB-2eceA:
undetectable		 4feuB-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.16A 4feuF-2eceA:
undetectable		 4feuF-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.21A 4fevD-2eceA:
undetectable		 4fevD-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.19A 4fevF-2eceA:
undetectable		 4fevF-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.16A 4fewD-2eceA:
undetectable		 4fewD-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.16A 4fewF-2eceA:
undetectable		 4fewF-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.23A 4fexB-2eceA:
undetectable		 4fexB-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.20A 4gkhB-2eceA:
undetectable		 4gkhB-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.18A 4gkhG-2eceA:
undetectable		 4gkhG-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.17A 4gkiA-2eceA:
undetectable		 4gkiA-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 ASP A 192
ASP A 327
ASN A 270
ASP A 325
 None
 1.18A 4gkiC-2eceA:
undetectable		 4gkiC-2eceA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 THR A 398
LEU A 449
VAL A 447
VAL A 437
 None
 0.98A 4l4aA-2eceA:
undetectable		 4l4aA-2eceA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 THR A 398
LEU A 449
VAL A 447
VAL A 437
 None
 0.96A 4l4dA-2eceA:
undetectable		 4l4dA-2eceA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 THR A 398
LEU A 449
VAL A 447
VAL A 437
 None
 0.95A 4l4eA-2eceA:
undetectable		 4l4eA-2eceA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 THR A 398
LEU A 449
VAL A 447
VAL A 437
 None
 0.97A 4l4fA-2eceA:
undetectable		 4l4fA-2eceA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		3 / 3 ALA A 454
GLN A 347
GLY A 360
 None
 0.61A 4odoC-2eceA:
undetectable		 4odoC-2eceA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  99
GLY A  77
ALA A  31
VAL A 143
ILE A 152
 None
 1.14A 4rvgA-2eceA:
undetectable		 4rvgA-2eceA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 12 THR A 398
ILE A 152
PHE A 193
ASP A 327
GLU A 387
 None
 1.43A 4zjqD-2eceA:
undetectable		 4zjqD-2eceA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 7 ARG A 104
THR A  35
ASP A  43
GLY A 102
 None
 1.11A 5hwaA-2eceA:
undetectable		 5hwaA-2eceA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 12 SER A 400
HIS A 445
HIS A  74
LEU A 254
THR A 324
 None
 1.36A 5jnaB-2eceA:
undetectable		 5jnaB-2eceA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 4 LEU A 244
ARG A 240
ILE A 230
PHE A 232
 None
 1.32A 5kirB-2eceA:
undetectable		 5kirB-2eceA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A 209
TYR A 191
ILE A 230
SER A 243
HIS A 231
 None
 1.49A 5lsaA-2eceA:
undetectable		 5lsaA-2eceA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 6 ARG A 240
HIS A 231
LEU A 189
PRO A 163
 None
 1.26A 5syjA-2eceA:
undetectable		 5syjA-2eceA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 6 ARG A 240
HIS A 231
LEU A 189
PRO A 163
 None
 1.28A 5syjB-2eceA:
undetectable		 5syjB-2eceA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 8 GLY A 267
ASP A 332
ASP A 261
HIS A 260
 None
 0.84A 6ag0A-2eceA:
undetectable		 6ag0A-2eceA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 6 LYS A 314
PHE A 316
VAL A 319
PRO A 320
 None
 1.24A 6fgdA-2eceA:
undetectable		 6fgdA-2eceA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 2ece 462AA LONG
HYPOTHETICAL
SELENIUM-BINDING
PROTEIN
(Sulfurisphaera
tokodaii) 		4 / 4 HIS A 260
LEU A 449
TYR A 396
GLY A 392
 None
 1.48A 6n91B-2eceA:
undetectable		 6n91B-2eceA:
12.29