SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ed2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 2ed2 GENERAL
TRANSCRIPTION FACTOR
II-I
(Homo
sapiens) 		4 / 5 ILE A  53
PRO A  54
PHE A  55
ILE A  76
 None
 1.03A 2hjhA-2ed2A:
undetectable		 2hjhA-2ed2A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 2ed2 GENERAL
TRANSCRIPTION FACTOR
II-I
(Homo
sapiens) 		4 / 8 PHE A  55
CYH A  17
PHE A  20
PHE A  78
 None
 0.97A 3ko0O-2ed2A:
undetectable
3ko0Q-2ed2A:
undetectable		 3ko0O-2ed2A:
19.83
3ko0Q-2ed2A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2ed2 GENERAL
TRANSCRIPTION FACTOR
II-I
(Homo
sapiens) 		4 / 4 GLU A  67
PRO A  64
ILE A  63
LEU A   8
 None
 1.33A 5m45D-2ed2A:
undetectable		 5m45D-2ed2A:
9.01