SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ed6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 2ed6 25KDA STRUCTURAL
PROTEIN VP25
(White
spot
syndrome
virus) 		5 / 12 VAL A 196
VAL A 194
LEU A  52
ALA A  96
PHE A 122
 None
 0.99A 2gj5A-2ed6A:
undetectable		 2gj5A-2ed6A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ed6 25KDA STRUCTURAL
PROTEIN VP25
(White
spot
syndrome
virus) 		4 / 5 GLU A 165
THR A 128
THR A  46
HIS A  40
 None
 1.21A 5axaA-2ed6A:
undetectable		 5axaA-2ed6A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ed6 25KDA STRUCTURAL
PROTEIN VP25
(White
spot
syndrome
virus) 		4 / 5 GLU A 165
THR A 128
THR A  46
HIS A  40
 None
 1.24A 5axaC-2ed6A:
undetectable		 5axaC-2ed6A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2ed6 25KDA STRUCTURAL
PROTEIN VP25
(White
spot
syndrome
virus) 		5 / 12 PHE A 171
PHE A  65
GLY A 136
PHE A 177
MET A 192
 None
 1.29A 5v5zA-2ed6A:
undetectable		 5v5zA-2ed6A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2ed6 25KDA STRUCTURAL
PROTEIN VP25
(White
spot
syndrome
virus) 		4 / 8 GLY A 120
CYH A 173
GLY A 174
SER A 156
 None
 0.67A 5vw9A-2ed6A:
undetectable		 5vw9A-2ed6A:
18.69