SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2edm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGO_A_PCFA1213_0 (WNT INHIBITORY FACTOR 1)	2edm	22KDA STRUCTURAL PROTEIN VP22 (White spot syndrome virus)	5 / 12	LEU A 128 ILE A 130 ILE A 159 PHE A 189 VAL A 76	None	0.71A	2ygoA-2edmA: undetectable	2ygoA-2edmA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	2edm	22KDA STRUCTURAL PROTEIN VP22 (White spot syndrome virus)	4 / 5	ILE A 96 ARG A 64 MET A 185 THR A 184	None	1.35A	3abkN-2edmA: undetectable 3abkW-2edmA: undetectable	3abkN-2edmA: 15.27 3abkW-2edmA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_A_LEUA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	2edm	22KDA STRUCTURAL PROTEIN VP22 (White spot syndrome virus)	4 / 6	THR A 138 ALA A 183 THR A 184 VAL A 135	None	0.98A	5ecoA-2edmA: undetectable	5ecoA-2edmA: 13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H7M_B_68HB405_0 (BETA-1 ADRENERGIC RECEPTOR)	2edm	22KDA STRUCTURAL PROTEIN VP22 (White spot syndrome virus)	5 / 12	VAL A 135 SER A 114 SER A 173 PHE A 181 PHE A 175	None	1.37A	6h7mB-2edmA: undetectable	6h7mB-2edmA: 18.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YGO_A_PCFA1213_0","WNT INHIBITORY FACTOR 1","2edm","22KDA STRUCTURAL PROTEIN VP22","White spot syndrome virus",5,"LEU A 128;ILE A 130;ILE A 159;PHE A 189;VAL A  76","None","0.71A","2ygoA-2edmA:undetectable","2ygoA-2edmA:21.69"],["3ABK_W_CHDW1059_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","2edm","22KDA STRUCTURAL PROTEIN VP22","White spot syndrome virus",4,"ILE A  96;ARG A  64;MET A 185;THR A 184","None","1.35A","3abkN-2edmA:undetectable;3abkW-2edmA:undetectable","3abkN-2edmA:15.27;3abkW-2edmA:17.72"],["5ECO_A_LEUA602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","2edm","22KDA STRUCTURAL PROTEIN VP22","White spot syndrome virus",4,"THR A 138;ALA A 183;THR A 184;VAL A 135","None","0.98A","5ecoA-2edmA:undetectable","5ecoA-2edmA:13.81"],["6H7M_B_68HB405_0","BETA-1 ADRENERGIC RECEPTOR","2edm","22KDA STRUCTURAL PROTEIN VP22","White spot syndrome virus",5,"VAL A 135;SER A 114;SER A 173;PHE A 181;PHE A 175","None","1.37A","6h7mB-2edmA:undetectable","6h7mB-2edmA:18.52"]]