SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ee2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 2ee2 CONTACTIN-1
(Homo
sapiens) 		5 / 10 ILE A  52
VAL A  27
VAL A  25
GLY A  26
LEU A  78
 None
 1.37A 1s1uA-2ee2A:
undetectable		 1s1uA-2ee2A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2ee2 CONTACTIN-1
(Homo
sapiens) 		4 / 6 SER A 103
GLY A  26
ILE A  52
TRP A  39
 None
 1.05A 5j4nA-2ee2A:
undetectable		 5j4nA-2ee2A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2ee2 CONTACTIN-1
(Homo
sapiens) 		3 / 3 ILE A 106
VAL A  25
PRO A  22
 None
 0.72A 5uunA-2ee2A:
undetectable		 5uunA-2ee2A:
17.24