SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eel'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1N_A_CAMA1422_0 (CYTOCHROME P450-CAM)	2eel	CELL DEATH ACTIVATOR CIDE-A (Homo sapiens)	5 / 11	LEU A 47 VAL A 48 VAL A 58 ASP A 60 VAL A 51	None	1.27A	2a1nA-2eelA: undetectable	2a1nA-2eelA: 13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CP4_A_CAMA416_0 (CYTOCHROME P450-CAM)	2eel	CELL DEATH ACTIVATOR CIDE-A (Homo sapiens)	5 / 10	LEU A 47 VAL A 48 VAL A 58 ASP A 60 VAL A 51	None	1.20A	2cp4A-2eelA: undetectable	2cp4A-2eelA: 13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_A_CHDA1503_0 (FERROCHELATASE, MITOCHONDRIAL)	2eel	CELL DEATH ACTIVATOR CIDE-A (Homo sapiens)	4 / 8	ILE A 76 LEU A 50 VAL A 25 GLY A 24	None	0.88A	3w1wA-2eelA: undetectable	3w1wA-2eelA: 11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X3M_A_ADNA301_1 (RNA 2'-O RIBOSE METHYLTRANSFERASE)	2eel	CELL DEATH ACTIVATOR CIDE-A (Homo sapiens)	5 / 9	LEU A 33 ILE A 76 SER A 15 VAL A 25 THR A 37	None	1.35A	4x3mA-2eelA: undetectable	4x3mA-2eelA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G5G_C_ACTC1740_0 (PUTATIVE XANTHINE DEHYDROGENASE YAGS FAD-BINDING SUBUNIT)	2eel	CELL DEATH ACTIVATOR CIDE-A (Homo sapiens)	4 / 4	VAL A 48 GLU A 78 GLY A 46 LEU A 38	None	1.19A	5g5gC-2eelA: undetectable	5g5gC-2eelA: 9.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2A1N_A_CAMA1422_0","CYTOCHROME P450-CAM","2eel","CELL DEATH ACTIVATOR CIDE-A","Homo sapiens",5,"LEU A  47;VAL A  48;VAL A  58;ASP A  60;VAL A  51","None","1.27A","2a1nA-2eelA:undetectable","2a1nA-2eelA:13.53"],["2CP4_A_CAMA416_0","CYTOCHROME P450-CAM","2eel","CELL DEATH ACTIVATOR CIDE-A","Homo sapiens",5,"LEU A  47;VAL A  48;VAL A  58;ASP A  60;VAL A  51","None","1.20A","2cp4A-2eelA:undetectable","2cp4A-2eelA:13.57"],["3W1W_A_CHDA1503_0","FERROCHELATASE, MITOCHONDRIAL","2eel","CELL DEATH ACTIVATOR CIDE-A","Homo sapiens",4,"ILE A  76;LEU A  50;VAL A  25;GLY A  24","None","0.88A","3w1wA-2eelA:undetectable","3w1wA-2eelA:11.65"],["4X3M_A_ADNA301_1","RNA 2'-O RIBOSE METHYLTRANSFERASE","2eel","CELL DEATH ACTIVATOR CIDE-A","Homo sapiens",5,"LEU A  33;ILE A  76;SER A  15;VAL A  25;THR A  37","None","1.35A","4x3mA-2eelA:undetectable","4x3mA-2eelA:16.29"],["5G5G_C_ACTC1740_0","PUTATIVE XANTHINE DEHYDROGENASE YAGS FAD-BINDING SUBUNIT","2eel","CELL DEATH ACTIVATOR CIDE-A","Homo sapiens",4,"VAL A  48;GLU A  78;GLY A  46;LEU A  38","None","1.19A","5g5gC-2eelA:undetectable","5g5gC-2eelA:9.92"]]