SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eeo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2eeo ASPARTATE
1-DECARBOXYLASE
(Thermus
thermophilus) 		5 / 10 ILE B  71
ASP B  48
ASN B 112
ILE A  10
ILE B  69
 None
 1.30A 1j3jA-2eeoB:
undetectable		 1j3jA-2eeoB:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2eeo ASPARTATE
1-DECARBOXYLASE
(Thermus
thermophilus) 		4 / 7 THR B  57
LEU B  55
VAL B  79
ILE B  69
 FUM  B 501 ( 3.6A)
None
None
None
 0.94A 1t87B-2eeoB:
undetectable		 1t87B-2eeoB:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 2eeo ASPARTATE
1-DECARBOXYLASE
ASPARTATE
1-DECARBOXYLASE
(Thermus
thermophilus;
Thermus
thermophilus) 		5 / 9 THR B  57
LEU B  55
VAL B  79
ILE B  69
VAL A  15
 FUM  B 501 ( 3.6A)
None
None
None
None
 1.46A 2l8mA-2eeoB:
undetectable		 2l8mA-2eeoB:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 2eeo ASPARTATE
1-DECARBOXYLASE
(Thermus
thermophilus) 		4 / 7 ILE B  49
LEU B  87
THR A  16
ARG B 113
 None
 1.07A 3nxuA-2eeoB:
undetectable		 3nxuA-2eeoB:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 2eeo ASPARTATE
1-DECARBOXYLASE
(Thermus
thermophilus) 		4 / 7 ILE B  49
LEU B  87
THR A  16
ARG B 113
 None
 1.04A 5vc0A-2eeoB:
undetectable		 5vc0A-2eeoB:
11.30