SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eey'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 2eey MOLYBDOPTERIN
BIOSYNTHESIS
(Geobacillus
kaustophilus) 		4 / 8 ASP A  17
ILE A  18
THR A  19
PRO A  78
 None
 0.93A 1hmyA-2eeyA:
undetectable		 1hmyA-2eeyA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2eey MOLYBDOPTERIN
BIOSYNTHESIS
(Geobacillus
kaustophilus) 		5 / 10 ALA A 103
THR A 104
ALA A  28
ALA A  30
ALA A  66
 None
 1.06A 2f16K-2eeyA:
undetectable
2f16L-2eeyA:
undetectable		 2f16K-2eeyA:
21.17
2f16L-2eeyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2eey MOLYBDOPTERIN
BIOSYNTHESIS
(Geobacillus
kaustophilus) 		5 / 10 ALA A 103
THR A 104
ALA A  28
ALA A  30
ALA A  66
 None
 1.06A 2f16Y-2eeyA:
undetectable
2f16Z-2eeyA:
undetectable		 2f16Y-2eeyA:
21.17
2f16Z-2eeyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2eey MOLYBDOPTERIN
BIOSYNTHESIS
(Geobacillus
kaustophilus) 		3 / 3 ASP A 130
TYR A 129
LYS A 137
 None
 0.98A 2othA-2eeyA:
undetectable		 2othA-2eeyA:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 2eey MOLYBDOPTERIN
BIOSYNTHESIS
(Geobacillus
kaustophilus) 		3 / 3 TYR A 129
LYS A 137
LYS A 133
 None
 0.99A 5dbyA-2eeyA:
2.3		 5dbyA-2eeyA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2eey MOLYBDOPTERIN
BIOSYNTHESIS
(Geobacillus
kaustophilus) 		5 / 9 ALA A 103
THR A 104
ALA A  28
ALA A  30
ALA A  66
 None
 1.08A 5l5zK-2eeyA:
undetectable
5l5zL-2eeyA:
undetectable		 5l5zK-2eeyA:
21.30
5l5zL-2eeyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2eey MOLYBDOPTERIN
BIOSYNTHESIS
(Geobacillus
kaustophilus) 		5 / 9 ALA A 103
THR A 104
ALA A  28
ALA A  30
ALA A  66
 None
 1.07A 5l5zY-2eeyA:
undetectable
5l5zZ-2eeyA:
undetectable		 5l5zY-2eeyA:
21.30
5l5zZ-2eeyA:
21.46