SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ef7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 9 GLY A 108
VAL A  41
PRO A  46
ILE A  39
VAL A  38
 None
 1.09A 2nnhB-2ef7A:
undetectable		 2nnhB-2ef7A:
14.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		6 / 12 ILE A  49
THR A  51
ASP A  54
LYS A  57
THR A  74
ILE A  98
 None
 1.10A 3kpbA-2ef7A:
14.5		 3kpbA-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 12 HIS A 100
ILE A  49
THR A  74
ILE A  98
PRO A 102
 None
 1.10A 3kpbC-2ef7A:
14.6		 3kpbC-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  49
ASP A  54
THR A  74
ILE A  98
PRO A 102
 None
 1.09A 3kpbC-2ef7A:
14.6		 3kpbC-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		6 / 12 ILE A  49
THR A  51
ASP A  54
LYS A  57
THR A  74
ILE A  98
 None
 1.13A 3kpbC-2ef7A:
14.6		 3kpbC-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		6 / 10 ILE A  49
THR A  51
ASP A  54
LYS A  57
THR A  74
ILE A  98
 None
 1.10A 3kpbD-2ef7A:
14.6		 3kpbD-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 11 ILE A  49
THR A  51
ASP A  54
THR A  74
ILE A  98
 None
 0.66A 3kpcA-2ef7A:
14.8		 3kpcA-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  49
ASP A  54
THR A  74
ILE A  98
PRO A 102
 None
 1.10A 3kpdB-2ef7A:
14.0		 3kpdB-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  49
THR A  51
ASP A  54
THR A  74
ILE A  98
 None
 0.59A 3kpdB-2ef7A:
14.0		 3kpdB-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  49
THR A  51
LYS A  57
THR A  74
ILE A  98
 None
 1.04A 3kpdB-2ef7A:
14.0		 3kpdB-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  49
THR A  51
ASP A  54
THR A  74
ILE A  98
 None
 0.69A 3kpdC-2ef7A:
14.2		 3kpdC-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  49
THR A  74
ASN A  97
ILE A  98
PRO A 102
 None
 1.03A 3kpdC-2ef7A:
14.2		 3kpdC-2ef7A:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2ef7 HYPOTHETICAL PROTEIN
ST2348
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A  14
ILE A  15
ASN A  34
ILE A  35
VAL A  38
 None
 0.53A 3kpdC-2ef7A:
14.2		 3kpdC-2ef7A:
33.58