SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ISM_A_NCAA303_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		6 / 9 TRP A 129
LEU A 149
ASP A 159
TRP A 193
SER A 197
GLU A 230
 None
 0.92A 1ismA-2eg9A:
9.1		 1ismA-2eg9A:
32.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 7 TRP A 129
LEU A 149
ASP A 159
TRP A 193
 None
 0.86A 1ismB-2eg9A:
9.5		 1ismB-2eg9A:
32.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		3 / 3 TRP A 163
PHE A 192
TRP A 193
 None
 0.35A 1r15C-2eg9A:
9.0		 1r15C-2eg9A:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		3 / 3 TRP A 163
PHE A 192
TRP A 193
 None
 0.33A 1r15F-2eg9A:
8.8		 1r15F-2eg9A:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		3 / 3 TRP A 163
PHE A 192
TRP A 193
 None
 0.34A 1r15G-2eg9A:
9.0		 1r15G-2eg9A:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		3 / 3 TRP A 163
PHE A 192
TRP A 193
 None
 0.35A 1r15H-2eg9A:
9.2		 1r15H-2eg9A:
31.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 6 TYR A  73
LYS A 125
PHE A 147
PRO A 122
 None
 1.47A 2vmyA-2eg9A:
undetectable		 2vmyA-2eg9A:
19.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		5 / 7 LEU A 149
GLU A 150
ASP A 159
TRP A 193
SER A 197
 None
 0.56A 3dzgA-2eg9A:
11.6		 3dzgA-2eg9A:
54.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		5 / 7 TRP A 129
LEU A 149
GLU A 150
TRP A 193
SER A 197
 None
 0.68A 3dzgA-2eg9A:
11.6		 3dzgA-2eg9A:
54.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		5 / 7 LEU A 149
GLU A 150
ASP A 159
TRP A 193
SER A 197
 None
 0.59A 3dzgB-2eg9A:
11.1		 3dzgB-2eg9A:
54.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		6 / 7 TRP A 129
LEU A 149
GLU A 150
TRP A 193
SER A 197
THR A 225
 None
 0.88A 3dzgB-2eg9A:
11.1		 3dzgB-2eg9A:
54.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 6 LEU A 149
GLU A 150
TRP A 193
SER A 197
 None
 0.46A 3i9jB-2eg9A:
9.7		 3i9jB-2eg9A:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		5 / 6 TRP A 129
LEU A 149
GLU A 150
TRP A 193
SER A 197
 None
 0.69A 3ropA-2eg9A:
12.5		 3ropA-2eg9A:
53.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 6 TRP A 129
LEU A 149
SER A 197
THR A 225
 None
 0.85A 3ropA-2eg9A:
12.5		 3ropA-2eg9A:
53.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 8 ASN A 187
PRO A 188
PHE A  97
TRP A  53
 None
 1.39A 4v30B-2eg9A:
undetectable		 4v30B-2eg9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 7 ASN A 187
PRO A 188
PHE A  97
TRP A  53
 None
 1.13A 5amhA-2eg9A:
0.0		 5amhA-2eg9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 8 ASN A 187
PRO A 188
PHE A  97
TRP A  53
 None
 1.40A 5amkA-2eg9A:
undetectable		 5amkA-2eg9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		3 / 3 PRO A 219
ILE A 250
SER A 261
 None
 0.80A 5fsaA-2eg9A:
undetectable		 5fsaA-2eg9A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 8 THR A 118
LEU A 153
ILE A  89
LEU A 154
 None
 0.83A 5g48A-2eg9A:
undetectable		 5g48A-2eg9A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		3 / 3 VAL A 246
SER A 259
MET A 268
 None
 0.87A 5ikqA-2eg9A:
undetectable		 5ikqA-2eg9A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 7 ASN A 187
PRO A 188
PHE A  97
TRP A  53
 None
 1.34A 5oh1A-2eg9A:
undetectable		 5oh1A-2eg9A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 7 ASN A 187
PRO A 188
PHE A  97
TRP A  53
 None
 1.35A 5oh1B-2eg9A:
undetectable		 5oh1B-2eg9A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		4 / 4 PHE A 277
LEU A 127
LEU A 212
VAL A 208
 None
 1.13A 5xxiA-2eg9A:
undetectable		 5xxiA-2eg9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2eg9 ADP-RIBOSYL CYCLASE
1
(Mus
musculus) 		5 / 12 ILE A 189
THR A 190
VAL A 114
SER A 197
GLU A 150
 None
 1.34A 6bzoC-2eg9A:
undetectable		 6bzoC-2eg9A:
11.30