SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2egg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		5 / 11 LEU A 181
GLU A 184
TYR A 157
ARG A 154
PHE A 158
 None
 1.42A 1l5rA-2eggA:
2.6		 1l5rA-2eggA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 7 THR A 246
LEU A 249
VAL A 236
ILE A 147
 None
 0.97A 1t87B-2eggA:
undetectable		 1t87B-2eggA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 7 ALA A  70
ILE A  69
ILE A  29
PHE A  58
 None
 0.93A 1upfB-2eggA:
4.1		 1upfB-2eggA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 5 PRO A  39
ILE A  29
GLY A  27
TYR A  55
 None
 1.18A 2jkjD-2eggA:
undetectable		 2jkjD-2eggA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 5 PRO A  39
ILE A  29
GLY A  27
TYR A  55
 None
 1.18A 2jkjF-2eggA:
undetectable		 2jkjF-2eggA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		5 / 12 ILE A  29
THR A  83
LEU A  28
VAL A  72
LEU A 117
 None
 1.23A 2jn3A-2eggA:
undetectable		 2jn3A-2eggA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		3 / 3 ARG A 173
VAL A 146
THR A 211
 None
 0.78A 2nmzA-2eggA:
undetectable		 2nmzA-2eggA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		3 / 3 ARG A 173
VAL A 146
THR A 211
 None
 0.82A 2nnkA-2eggA:
undetectable		 2nnkA-2eggA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 6 ARG A 201
ASP A 169
ILE A 168
GLU A 166
 None
 1.28A 2ya7C-2eggA:
undetectable		 2ya7C-2eggA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 6 ASP A 206
ARG A 231
ILE A 235
ARG A 258
 None
 1.34A 3ckzA-2eggA:
undetectable		 3ckzA-2eggA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 8 PRO A  85
SER A  59
GLY A  30
PRO A  62
 None
 0.94A 3lslA-2eggA:
undetectable
3lslD-2eggA:
3.3		 3lslA-2eggA:
21.97
3lslD-2eggA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		3 / 3 ARG A 173
VAL A 146
THR A 211
 None
 0.84A 3nduD-2eggA:
undetectable		 3nduD-2eggA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		3 / 3 ARG A 173
VAL A 146
THR A 211
 None
 0.81A 3pwrA-2eggA:
undetectable		 3pwrA-2eggA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		3 / 3 ARG A 173
VAL A 146
THR A 211
 None
 0.84A 3tl9A-2eggA:
undetectable		 3tl9A-2eggA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		5 / 12 THR A 122
ASN A 108
GLY A 152
GLY A 264
ASN A 261
 None
 1.12A 3v3oA-2eggA:
undetectable		 3v3oA-2eggA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 7 ASN A 172
ALA A 178
VAL A 146
THR A 212
 None
 0.98A 4eyrA-2eggA:
undetectable		 4eyrA-2eggA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 8 ILE A 110
ILE A  29
ALA A  68
VAL A  90
 None
 0.73A 4jltA-2eggA:
undetectable		 4jltA-2eggA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 6 ASP A 123
ALA A 101
THR A 122
THR A 109
 None
 1.42A 4w5tA-2eggA:
undetectable		 4w5tA-2eggA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		4 / 6 ASP A 123
ALA A 101
THR A 122
THR A 109
 None
 1.42A 4z4fA-2eggA:
undetectable		 4z4fA-2eggA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		3 / 3 LEU A  28
THR A 122
ASN A 121
 None
 0.61A 6baaE-2eggA:
undetectable		 6baaE-2eggA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		3 / 3 LEU A  28
THR A 122
ASN A 121
 None
 0.61A 6baaF-2eggA:
undetectable		 6baaF-2eggA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		3 / 3 LEU A  28
THR A 122
ASN A 121
 None
 0.62A 6baaG-2eggA:
undetectable		 6baaG-2eggA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2egg SHIKIMATE
5-DEHYDROGENASE
(Geobacillus
kaustophilus) 		3 / 3 LEU A  28
THR A 122
ASN A 121
 None
 0.62A 6baaH-2eggA:
undetectable		 6baaH-2eggA:
11.83