SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2egp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_A_ACTA3003_0 (BETA-CARBONIC ANHYDRASE)	2egp	TRIPARTITE MOTIF-CONTAINING PROTEIN 34 (Homo sapiens)	4 / 8	CYH A 59 VAL A 58 CYH A 30 GLY A 31	ZN A 400 (-2.3A) ZN A 400 ( 4.6A) ZN A 400 (-2.3A) None	0.92A	1ekjA-2egpA: undetectable 1ekjB-2egpA: undetectable	1ekjA-2egpA: 14.55 1ekjB-2egpA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGO_A_PCFA1213_1 (WNT INHIBITORY FACTOR 1)	2egp	TRIPARTITE MOTIF-CONTAINING PROTEIN 34 (Homo sapiens)	4 / 6	LEU A 34 ILE A 39 PRO A 57 VAL A 78	None	1.06A	2ygoA-2egpA: undetectable	2ygoA-2egpA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HRQ_C_IPHC101_0 (INSULIN A-CHAIN INSULIN B-CHAIN)	2egp	TRIPARTITE MOTIF-CONTAINING PROTEIN 34 (Homo sapiens)	4 / 5	CYH A 35 ILE A 39 CYH A 38 LEU A 22	ZN A 200 (-2.2A) None ZN A 200 (-2.2A) None	1.39A	5hrqC-2egpA: undetectable 5hrqD-2egpA: undetectable 5hrqL-2egpA: undetectable	5hrqC-2egpA: 13.92 5hrqD-2egpA: 13.92 5hrqL-2egpA: 13.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EKJ_A_ACTA3003_0","BETA-CARBONIC ANHYDRASE","2egp","TRIPARTITE MOTIF-CONTAINING PROTEIN 34","Homo sapiens",4,"CYH A  59;VAL A  58;CYH A  30;GLY A  31"," ZN A 400 (-2.3A); ZN A 400 ( 4.6A); ZN A 400 (-2.3A);None","0.92A","1ekjA-2egpA:undetectable;1ekjB-2egpA:undetectable","1ekjA-2egpA:14.55;1ekjB-2egpA:14.55"],["2YGO_A_PCFA1213_1","WNT INHIBITORY FACTOR 1","2egp","TRIPARTITE MOTIF-CONTAINING PROTEIN 34","Homo sapiens",4,"LEU A  34;ILE A  39;PRO A  57;VAL A  78","None","1.06A","2ygoA-2egpA:undetectable","2ygoA-2egpA:19.28"],["5HRQ_C_IPHC101_0","INSULIN A-CHAIN;INSULIN B-CHAIN","2egp","TRIPARTITE MOTIF-CONTAINING PROTEIN 34","Homo sapiens",4,"CYH A  35;ILE A  39;CYH A  38;LEU A  22"," ZN A 200 (-2.2A);None; ZN A 200 (-2.2A);None","1.39A","5hrqC-2egpA:undetectable;5hrqD-2egpA:undetectable;5hrqL-2egpA:undetectable","5hrqC-2egpA:13.92;5hrqD-2egpA:13.92;5hrqL-2egpA:13.92"]]