SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2egr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		5 / 8 LYS A 127
PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 1.30A 2eilP-2egrA:
undetectable
2eilW-2egrA:
undetectable		 2eilP-2egrA:
18.08
2eilW-2egrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		4 / 5 PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 1.10A 5xdqC-2egrA:
undetectable
5xdqJ-2egrA:
undetectable		 5xdqC-2egrA:
18.08
5xdqJ-2egrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		4 / 5 PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 1.08A 5xdqP-2egrA:
undetectable
5xdqW-2egrA:
undetectable		 5xdqP-2egrA:
18.08
5xdqW-2egrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		4 / 6 PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 1.02A 5z84P-2egrA:
undetectable
5z84W-2egrA:
undetectable		 5z84P-2egrA:
18.08
5z84W-2egrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		4 / 6 PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 0.98A 5z85P-2egrA:
undetectable
5z85W-2egrA:
undetectable		 5z85P-2egrA:
18.08
5z85W-2egrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		4 / 6 PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 1.05A 5z86C-2egrA:
undetectable
5z86J-2egrA:
undetectable		 5z86C-2egrA:
18.08
5z86J-2egrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		4 / 6 PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 1.03A 5z86P-2egrA:
undetectable
5z86W-2egrA:
undetectable		 5z86P-2egrA:
18.08
5z86W-2egrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		4 / 6 PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 1.06A 5zcoP-2egrA:
undetectable
5zcoW-2egrA:
undetectable		 5zcoP-2egrA:
18.08
5zcoW-2egrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		4 / 6 PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 1.10A 5zcpC-2egrA:
undetectable
5zcpJ-2egrA:
undetectable		 5zcpC-2egrA:
18.08
5zcpJ-2egrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2egr HYPOTHETICAL PROTEIN
AQ_1494
(Aquifex
aeolicus) 		4 / 6 PHE A  87
PHE A  89
LEU A  77
PHE A   3
 None
 1.02A 5zcpP-2egrA:
undetectable
5zcpW-2egrA:
undetectable		 5zcpP-2egrA:
18.08
5zcpW-2egrA:
22.00