SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eh0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.33A 1v8bA-2eh0A:
undetectable
1v8bA-2eh0A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.33A 1v8bB-2eh0A:
undetectable
1v8bB-2eh0A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.33A 1v8bC-2eh0A:
undetectable
1v8bC-2eh0A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.32A 1v8bD-2eh0A:
undetectable
1v8bD-2eh0A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.27A 2zj0A-2eh0A:
undetectable
2zj0A-2eh0A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
4 / 8 LEU A  74
ILE A 101
ARG A  96
GLY A  98
None
0.94A 3b9lA-2eh0A:
undetectable
3b9lA-2eh0A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.28A 3ce6A-2eh0A:
undetectable
3ce6A-2eh0A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.28A 3ce6C-2eh0A:
undetectable
3ce6C-2eh0A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.30A 3g1uA-2eh0A:
undetectable
3g1uA-2eh0A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.25A 3g1uB-2eh0A:
undetectable
3g1uB-2eh0A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.31A 3g1uD-2eh0A:
undetectable
3g1uD-2eh0A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.28A 3glqA-2eh0A:
undetectable
3glqA-2eh0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.30A 3glqB-2eh0A:
undetectable
3glqB-2eh0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 10 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.24A 3h9uA-2eh0A:
undetectable
3h9uA-2eh0A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 10 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.25A 3h9uC-2eh0A:
undetectable
3h9uC-2eh0A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 10 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.27A 3h9uD-2eh0A:
undetectable
3h9uD-2eh0A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.29A 3n58A-2eh0A:
undetectable
3n58A-2eh0A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
4 / 7 LEU A  95
SER A  62
THR A  33
VAL A  35
None
1.01A 3ozkB-2eh0A:
undetectable
3ozkB-2eh0A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
4 / 6 SER A  80
HIS A 107
MET A 103
THR A  82
None
1.34A 3thrB-2eh0A:
undetectable
3thrB-2eh0A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 ILE A 101
PHE A 111
GLN A  94
LEU A  74
ILE A  32
None
1.03A 4g1bD-2eh0A:
undetectable
4g1bD-2eh0A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.27A 4lvcA-2eh0A:
undetectable
4lvcA-2eh0A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.29A 4lvcC-2eh0A:
undetectable
4lvcC-2eh0A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.32A 4pfjA-2eh0A:
undetectable
4pfjA-2eh0A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.25A 5axaA-2eh0A:
undetectable
5axaA-2eh0A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.27A 5axaC-2eh0A:
undetectable
5axaC-2eh0A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.28A 5hm8A-2eh0A:
undetectable
5hm8A-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.28A 5hm8B-2eh0A:
undetectable
5hm8B-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.29A 5hm8C-2eh0A:
undetectable
5hm8C-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.29A 5hm8D-2eh0A:
undetectable
5hm8D-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.29A 5hm8E-2eh0A:
undetectable
5hm8E-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.29A 5hm8F-2eh0A:
undetectable
5hm8F-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.28A 5hm8G-2eh0A:
undetectable
5hm8G-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.28A 5hm8H-2eh0A:
undetectable
5hm8H-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.26A 5m5kA-2eh0A:
undetectable
5m5kA-2eh0A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.24A 5m5kC-2eh0A:
undetectable
5m5kC-2eh0A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.28A 5m66A-2eh0A:
undetectable
5m66A-2eh0A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.24A 5m66B-2eh0A:
undetectable
5m66B-2eh0A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.28A 5utuF-2eh0A:
undetectable
5utuF-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.27A 5utuH-2eh0A:
undetectable
5utuH-2eh0A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.26A 5v96A-2eh0A:
undetectable
5v96A-2eh0A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.26A 5v96B-2eh0A:
undetectable
5v96B-2eh0A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.27A 5v96C-2eh0A:
undetectable
5v96C-2eh0A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.26A 5v96D-2eh0A:
undetectable
5v96D-2eh0A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 THR A  82
VAL A  12
LEU A  11
PHE A  60
ASN A  99
None
1.15A 6drzA-2eh0A:
undetectable
6drzA-2eh0A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.31A 6gbnA-2eh0A:
undetectable
6gbnA-2eh0A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo
sapiens)
5 / 12 LEU A  11
LEU A  48
GLY A  36
HIS A  57
PHE A  60
None
1.29A 6gbnD-2eh0A:
undetectable
6gbnD-2eh0A:
13.82