SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eh7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
None
1.10A 1usqA-2eh7H:
undetectable
1usqA-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
None
0.80A 1usqB-2eh7H:
undetectable
1usqB-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
None
0.80A 1usqC-2eh7H:
undetectable
1usqC-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
None
0.81A 1usqD-2eh7H:
undetectable
1usqD-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
None
0.81A 1usqE-2eh7H:
undetectable
1usqE-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
None
1.09A 1usqF-2eh7H:
undetectable
1usqF-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
None
0.87A 2jkjB-2eh7H:
undetectable
2jkjB-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
None
1.12A 2jkjE-2eh7H:
undetectable
2jkjE-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
None
1.12A 2jklA-2eh7H:
undetectable
2jklA-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
None
1.12A 2jklC-2eh7H:
undetectable
2jklC-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
None
1.12A 2jklD-2eh7H:
undetectable
2jklD-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
None
1.12A 2jklE-2eh7H:
undetectable
2jklE-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
None
1.12A 2jklF-2eh7H:
undetectable
2jklF-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
4 / 6 LEU H 189
GLY H 190
ALA H 125
PRO H 126
None
0.46A 3huoA-2eh7H:
undetectable
3huoA-2eh7H:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.94A 4qvnH-2eh7H:
undetectable
4qvnI-2eh7H:
undetectable
4qvnH-2eh7H:
21.43
4qvnI-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 10 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.94A 4qvnV-2eh7H:
undetectable
4qvnW-2eh7H:
undetectable
4qvnV-2eh7H:
21.43
4qvnW-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.92A 4qvpH-2eh7H:
undetectable
4qvpI-2eh7H:
undetectable
4qvpH-2eh7H:
21.43
4qvpI-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.92A 4qvpV-2eh7H:
undetectable
4qvpW-2eh7H:
undetectable
4qvpV-2eh7H:
21.43
4qvpW-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.94A 4qvqH-2eh7H:
undetectable
4qvqI-2eh7H:
undetectable
4qvqH-2eh7H:
21.43
4qvqI-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.93A 4qvqV-2eh7H:
undetectable
4qvqW-2eh7H:
undetectable
4qvqV-2eh7H:
21.43
4qvqW-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.95A 4qvvH-2eh7H:
undetectable
4qvvH-2eh7H:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.94A 4qvvV-2eh7H:
undetectable
4qvvV-2eh7H:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.93A 4qvyH-2eh7H:
undetectable
4qvyH-2eh7H:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.93A 4qvyV-2eh7H:
undetectable
4qvyW-2eh7H:
undetectable
4qvyV-2eh7H:
21.43
4qvyW-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.94A 4qw0H-2eh7H:
undetectable
4qw0I-2eh7H:
undetectable
4qw0H-2eh7H:
21.43
4qw0I-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.94A 4qw0V-2eh7H:
undetectable
4qw0W-2eh7H:
undetectable
4qw0V-2eh7H:
21.43
4qw0W-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.95A 4qw1H-2eh7H:
undetectable
4qw1I-2eh7H:
undetectable
4qw1H-2eh7H:
21.43
4qw1I-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.95A 4qw1V-2eh7H:
undetectable
4qw1W-2eh7H:
undetectable
4qw1V-2eh7H:
21.43
4qw1W-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.94A 4qwuH-2eh7H:
undetectable
4qwuI-2eh7H:
undetectable
4qwuH-2eh7H:
21.43
4qwuI-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.94A 4qwuV-2eh7H:
undetectable
4qwuW-2eh7H:
undetectable
4qwuV-2eh7H:
21.43
4qwuW-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.93A 5bxnH-2eh7H:
undetectable
5bxnI-2eh7H:
undetectable
5bxnH-2eh7H:
21.43
5bxnI-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.94A 5cz7V-2eh7H:
undetectable
5cz7W-2eh7H:
undetectable
5cz7V-2eh7H:
21.43
5cz7W-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.92A 5d0xV-2eh7H:
undetectable
5d0xV-2eh7H:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.90A 5l5fH-2eh7H:
undetectable
5l5fI-2eh7H:
undetectable
5l5fH-2eh7H:
21.43
5l5fI-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
0.90A 5l5fV-2eh7H:
undetectable
5l5fW-2eh7H:
undetectable
5l5fV-2eh7H:
21.43
5l5fW-2eh7H:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 12 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
1.01A 6hwdH-2eh7H:
undetectable
6hwdI-2eh7H:
undetectable
6hwdH-2eh7H:
19.90
6hwdI-2eh7H:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus
musculus)
5 / 11 SER H 188
GLY H 134
THR H 135
ALA H 136
THR H 131
None
1.01A 6hwdV-2eh7H:
undetectable
6hwdV-2eh7H:
19.90