SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eho'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 2eho GINS COMPLEX SUBUNIT
3
(Homo
sapiens) 		3 / 3 SER D 152
GLU D 172
ASP D 108
 None
 0.69A 2avdB-2ehoD:
undetectable		 2avdB-2ehoD:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 2eho GINS COMPLEX SUBUNIT
3
(Homo
sapiens) 		3 / 3 GLY D  14
PRO D  15
GLN D 122
 None
 0.59A 4qwpB-2ehoD:
undetectable		 4qwpB-2ehoD:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 2eho GINS COMPLEX SUBUNIT
3
(Homo
sapiens) 		3 / 3 ARG D  97
GLN D  93
GLU D 130
 None
 0.80A 4tvtA-2ehoD:
undetectable		 4tvtA-2ehoD:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 2eho GINS COMPLEX SUBUNIT
3
(Homo
sapiens) 		5 / 12 ILE D 134
PRO D  33
GLU D  67
GLU D 130
TYR D  92
 None
 1.35A 5mqtC-2ehoD:
undetectable		 5mqtC-2ehoD:
20.75