SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ehr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 2ehr INAD-LIKE PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  75
GLY A  36
VAL A  92
SER A  89
PHE A 104
 None
 1.26A 1sg9A-2ehrA:
undetectable		 1sg9A-2ehrA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 2ehr INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 8 VAL A 102
GLY A  30
GLY A  64
ALA A  63
 None
 0.69A 3aruA-2ehrA:
undetectable		 3aruA-2ehrA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2ehr INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  75
PHE A 104
SER A  87
GLU A  93
 None
 0.87A 3ua5A-2ehrA:
undetectable		 3ua5A-2ehrA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2ehr INAD-LIKE PROTEIN
(Homo
sapiens) 		4 / 4 ASP A  82
ILE A 105
PRO A  16
LEU A  76
 None
 1.48A 6mkeB-2ehrA:
undetectable		 6mkeB-2ehrA:
20.33