SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ehw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7C_A_HLTA4002_1 (SERUM ALBUMIN)	2ehw	HYPOTHETICAL PROTEIN TTHB059 (Thermus thermophilus)	4 / 5	ARG A 38 ALA A 8 LYS A 3 GLU A 5	None	0.91A	1e7cA-2ehwA: 3.4	1e7cA-2ehwA: 13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_F_ASDF1224_1 (GLUTATHIONE S-TRANSFERASE A3)	2ehw	HYPOTHETICAL PROTEIN TTHB059 (Thermus thermophilus)	4 / 8	LEU A 61 LEU A 64 LEU A 41 ALA A 8	None	0.86A	2vcvF-2ehwA: undetectable	2vcvF-2ehwA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_P_ASDP1224_1 (GLUTATHIONE S-TRANSFERASE A3)	2ehw	HYPOTHETICAL PROTEIN TTHB059 (Thermus thermophilus)	4 / 8	LEU A 61 LEU A 64 LEU A 41 ALA A 8	None	0.77A	2vcvP-2ehwA: undetectable	2vcvP-2ehwA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JQB_B_IBPB706_1 (ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1 ENVELOPE GLYCOPROTEIN 2)	2ehw	HYPOTHETICAL PROTEIN TTHB059 (Thermus thermophilus)	5 / 8	ALA A 86 LEU A 57 LEU A 61 LEU A 6 LEU A 9	None	1.27A	5jqbA-2ehwA: undetectable 5jqbB-2ehwA: undetectable	5jqbA-2ehwA: 18.63 5jqbB-2ehwA: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7C_A_HLTA4002_1","SERUM ALBUMIN","2ehw","HYPOTHETICAL PROTEIN TTHB059","Thermus thermophilus",4,"ARG A  38;ALA A   8;LYS A   3;GLU A   5","None","0.91A","1e7cA-2ehwA:3.4","1e7cA-2ehwA:13.44"],["2VCV_F_ASDF1224_1","GLUTATHIONE S-TRANSFERASE A3","2ehw","HYPOTHETICAL PROTEIN TTHB059","Thermus thermophilus",4,"LEU A  61;LEU A  64;LEU A  41;ALA A   8","None","0.86A","2vcvF-2ehwA:undetectable","2vcvF-2ehwA:22.52"],["2VCV_P_ASDP1224_1","GLUTATHIONE S-TRANSFERASE A3","2ehw","HYPOTHETICAL PROTEIN TTHB059","Thermus thermophilus",4,"LEU A  61;LEU A  64;LEU A  41;ALA A   8","None","0.77A","2vcvP-2ehwA:undetectable","2vcvP-2ehwA:22.52"],["5JQB_B_IBPB706_1","ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1;ENVELOPE GLYCOPROTEIN 2","2ehw","HYPOTHETICAL PROTEIN TTHB059","Thermus thermophilus",5,"ALA A  86;LEU A  57;LEU A  61;LEU A   6;LEU A   9","None","1.27A","5jqbA-2ehwA:undetectable;5jqbB-2ehwA:undetectable","5jqbA-2ehwA:18.63;5jqbB-2ehwA:21.43"]]