SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ei9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)
2ei9 NON-LTR
RETROTRANSPOSON
R1BMKS ORF2 PROTEIN

(Bombyx
mori)
5 / 8 HIS A 171
SER A 194
VAL A 198
GLY A 219
GLY A 221
None
1.32A 1aq7A-2ei9A:
undetectable
1aq7A-2ei9A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
2ei9 NON-LTR
RETROTRANSPOSON
R1BMKS ORF2 PROTEIN

(Bombyx
mori)
3 / 3 GLN A  54
ILE A  88
HIS A  87
None
0.73A 1fm9A-2ei9A:
undetectable
1fm9A-2ei9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)
2ei9 NON-LTR
RETROTRANSPOSON
R1BMKS ORF2 PROTEIN

(Bombyx
mori)
5 / 12 LEU A 113
LEU A 110
ALA A  98
ILE A 163
LEU A 168
None
1.08A 1tw4A-2ei9A:
undetectable
1tw4A-2ei9A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)
2ei9 NON-LTR
RETROTRANSPOSON
R1BMKS ORF2 PROTEIN

(Bombyx
mori)
4 / 6 ASN A 172
ILE A  16
GLN A  15
THR A 131
None
1.06A 2hkkA-2ei9A:
undetectable
2hkkA-2ei9A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)
2ei9 NON-LTR
RETROTRANSPOSON
R1BMKS ORF2 PROTEIN

(Bombyx
mori)
5 / 12 ALA A  73
GLY A  62
LEU A  52
LEU A  75
SER A  79
None
1.25A 2nv4B-2ei9A:
undetectable
2nv4B-2ei9A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)
2ei9 NON-LTR
RETROTRANSPOSON
R1BMKS ORF2 PROTEIN

(Bombyx
mori)
4 / 5 ALA A  98
VAL A  96
PHE A 100
ILE A 116
None
1.02A 5of1A-2ei9A:
undetectable
5of1A-2ei9A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)
2ei9 NON-LTR
RETROTRANSPOSON
R1BMKS ORF2 PROTEIN

(Bombyx
mori)
4 / 6 LEU A  52
VAL A  42
LEU A  18
VAL A  40
None
0.96A 5x7zA-2ei9A:
undetectable
5x7zA-2ei9A:
22.95