SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eia'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_D_TFPD207_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2eia	EIAV CAPSID PROTEIN P26 (Equine infectious anemia virus)	4 / 8	SER A 182 LEU A 211 PHE A 164 SER A 170	None	1.03A	1wrlC-2eiaA: undetectable 1wrlD-2eiaA: undetectable	1wrlC-2eiaA: 17.10 1wrlD-2eiaA: 17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_A_1FLA2003_1 (SERUM ALBUMIN)	2eia	EIAV CAPSID PROTEIN P26 (Equine infectious anemia virus)	5 / 9	TYR A 129 LEU A 32 LEU A 57 LEU A 71 ALA A 136	None	1.03A	2bxeA-2eiaA: undetectable	2bxeA-2eiaA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2003_1 (SERUM ALBUMIN)	2eia	EIAV CAPSID PROTEIN P26 (Equine infectious anemia virus)	5 / 10	TYR A 129 LEU A 32 LEU A 57 LEU A 71 ALA A 136	None	1.08A	2bxeB-2eiaA: undetectable	2bxeB-2eiaA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7T_A_5FWA1001_1 (SUPEROXIDE DISMUTASE [CU-ZN])	2eia	EIAV CAPSID PROTEIN P26 (Equine infectious anemia virus)	3 / 3	ASP A 75 LYS A 76 ASP A 79	None	0.79A	4a7tA-2eiaA: undetectable	4a7tA-2eiaA: 20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BQF_B_QPSB951_1 (ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC)	2eia	EIAV CAPSID PROTEIN P26 (Equine infectious anemia virus)	4 / 8	ARG A 114 GLU A 51 LYS A 17 ARG A 18	None	1.14A	4bqfB-2eiaA: undetectable	4bqfB-2eiaA: 12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSW_A_P06A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2eia	EIAV CAPSID PROTEIN P26 (Equine infectious anemia virus)	3 / 3	PHE A 106 ILE A 100 ASP A 123	None	0.64A	5cswA-2eiaA: undetectable	5cswA-2eiaA: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSW_B_P06B801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2eia	EIAV CAPSID PROTEIN P26 (Equine infectious anemia virus)	3 / 3	PHE A 106 ILE A 100 ASP A 123	None	0.64A	5cswB-2eiaA: undetectable	5cswB-2eiaA: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCE_A_RITA602_2 (CYTOCHROME P450 3A4)	2eia	EIAV CAPSID PROTEIN P26 (Equine infectious anemia virus)	4 / 6	ARG A 18 PHE A 41 ILE A 27 THR A 26	None	1.08A	5vceA-2eiaA: undetectable	5vceA-2eiaA: 20.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRL_D_TFPD207_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES;TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","2eia","EIAV CAPSID PROTEIN P26","Equine infectious anemia virus",4,"SER A 182;LEU A 211;PHE A 164;SER A 170","None","1.03A","1wrlC-2eiaA:undetectable;1wrlD-2eiaA:undetectable","1wrlC-2eiaA:17.10;1wrlD-2eiaA:17.10"],["2BXE_A_1FLA2003_1","SERUM ALBUMIN","2eia","EIAV CAPSID PROTEIN P26","Equine infectious anemia virus",5,"TYR A 129;LEU A  32;LEU A  57;LEU A  71;ALA A 136","None","1.03A","2bxeA-2eiaA:undetectable","2bxeA-2eiaA:16.67"],["2BXE_B_1FLB2003_1","SERUM ALBUMIN","2eia","EIAV CAPSID PROTEIN P26","Equine infectious anemia virus",5,"TYR A 129;LEU A  32;LEU A  57;LEU A  71;ALA A 136","None","1.08A","2bxeB-2eiaA:undetectable","2bxeB-2eiaA:16.67"],["4A7T_A_5FWA1001_1","SUPEROXIDE DISMUTASE [CU-ZN]","2eia","EIAV CAPSID PROTEIN P26","Equine infectious anemia virus",3,"ASP A  75;LYS A  76;ASP A  79","None","0.79A","4a7tA-2eiaA:undetectable","4a7tA-2eiaA:20.39"],["4BQF_B_QPSB951_1","ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC","2eia","EIAV CAPSID PROTEIN P26","Equine infectious anemia virus",4,"ARG A 114;GLU A  51;LYS A  17;ARG A  18","None","1.14A","4bqfB-2eiaA:undetectable","4bqfB-2eiaA:12.93"],["5CSW_A_P06A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","2eia","EIAV CAPSID PROTEIN P26","Equine infectious anemia virus",3,"PHE A 106;ILE A 100;ASP A 123","None","0.64A","5cswA-2eiaA:undetectable","5cswA-2eiaA:20.34"],["5CSW_B_P06B801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","2eia","EIAV CAPSID PROTEIN P26","Equine infectious anemia virus",3,"PHE A 106;ILE A 100;ASP A 123","None","0.64A","5cswB-2eiaA:undetectable","5cswB-2eiaA:20.34"],["5VCE_A_RITA602_2","CYTOCHROME P450 3A4","2eia","EIAV CAPSID PROTEIN P26","Equine infectious anemia virus",4,"ARG A  18;PHE A  41;ILE A  27;THR A  26","None","1.08A","5vceA-2eiaA:undetectable","5vceA-2eiaA:20.37"]]