SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eiz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 2eiz ANTI-LYSOZYME
ANTIBODY FV REGION
(Homo
sapiens) 		4 / 8 HIS A  34
TYR A  36
TYR A  49
SER A  91
 None
 0.95A 1i7zA-2eizA:
20.9		 1i7zA-2eizA:
64.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2eiz ANTI-LYSOZYME
ANTIBODY FV REGION
(Homo
sapiens) 		4 / 8 ASN A  32
ILE A  29
GLY A  68
GLY A  64
 None
 0.78A 1me7A-2eizA:
undetectable		 1me7A-2eizA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 2eiz ANTI-LYSOZYME
ANTIBODY FV REGION
(Homo
sapiens) 		5 / 9 LEU B  20
ILE B 107
GLY B 106
GLY B 104
SER B  79
 None
 1.06A 2qmmA-2eizB:
undetectable		 2qmmA-2eizB:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 2eiz ANTI-LYSOZYME
ANTIBODY FV REGION
(Homo
sapiens) 		3 / 3 TYR A  36
TYR B  47
GLY B 100
 None
 0.76A 3eteB-2eizA:
undetectable
3eteD-2eizA:
undetectable
3eteF-2eizA:
undetectable		 3eteB-2eizA:
10.32
3eteD-2eizA:
10.32
3eteF-2eizA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2eiz ANTI-LYSOZYME
ANTIBODY FV REGION
(Homo
sapiens) 		5 / 12 SER B  62
ILE B  37
ILE B  48
VAL B  67
LEU B  82
 None
 1.03A 3w67B-2eizB:
undetectable		 3w67B-2eizB:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 2eiz ANTI-LYSOZYME
ANTIBODY FV REGION
(Homo
sapiens) 		4 / 5 TYR B  50
ASN B  60
TYR B  59
ILE B  69
 None
 1.05A 4jtpA-2eizB:
undetectable		 4jtpA-2eizB:
19.15