SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ek6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 2ek6 RNA-BINDING PROTEIN
12
(Homo
sapiens) 		3 / 3 PHE A  62
LEU A  31
SER A  43
 None
 0.78A 1e7aA-2ek6A:
undetectable		 1e7aA-2ek6A:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 2ek6 RNA-BINDING PROTEIN
12
(Homo
sapiens) 		5 / 12 PHE A  23
GLY A  56
PRO A  54
ASN A  20
PHE A  34
 None
 1.14A 2zznB-2ek6A:
2.8		 2zznB-2ek6A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2ek6 RNA-BINDING PROTEIN
12
(Homo
sapiens) 		4 / 7 PHE A  62
SER A  88
VAL A  18
VAL A  72
 None
 1.32A 3n61A-2ek6A:
undetectable
3n61B-2ek6A:
undetectable		 3n61A-2ek6A:
11.29
3n61B-2ek6A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2ek6 RNA-BINDING PROTEIN
12
(Homo
sapiens) 		4 / 6 VAL A  18
VAL A  85
ILE A  80
LEU A  31
 None
 1.00A 4l1wB-2ek6A:
undetectable		 4l1wB-2ek6A:
14.56