SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eke'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 2eke SUMO-CONJUGATING
ENZYME UBC9
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  45
ILE A  60
ILE A  92
PHE A  77
LEU A  94
 None
 0.94A 1qhsA-2ekeA:
undetectable		 1qhsA-2ekeA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2eke UBIQUITIN-LIKE
PROTEIN SMT3
(Saccharomyces
cerevisiae) 		5 / 10 LEU C1081
ILE C1039
ASP C1087
LEU C1026
ILE C1024
 None
 0.95A 1yi4A-2ekeC:
undetectable		 1yi4A-2ekeC:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 2eke UBIQUITIN-LIKE
PROTEIN SMT3
(Saccharomyces
cerevisiae) 		3 / 3 ARG C1046
ARG C1047
PRO C1044
 None
 1.01A 2wljA-2ekeC:
undetectable		 2wljA-2ekeC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 2eke SUMO-CONJUGATING
ENZYME UBC9
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 151
PHE A  81
TYR A  58
 None
 0.89A 3ucjB-2ekeA:
undetectable		 3ucjB-2ekeA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 2eke SUMO-CONJUGATING
ENZYME UBC9
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 151
PHE A  81
TYR A  58
 None
 0.87A 3ucjA-2ekeA:
undetectable		 3ucjA-2ekeA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2eke SUMO-CONJUGATING
ENZYME UBC9
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  45
PRO A  21
LEU A 114
PHE A  24
GLY A  44
 None
 1.36A 5k7uA-2ekeA:
undetectable		 5k7uA-2ekeA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2eke UBIQUITIN-LIKE
PROTEIN SMT3
(Saccharomyces
cerevisiae) 		3 / 3 LYS C1027
LEU C1045
ILE C1024
 None
 0.76A 5kc0A-2ekeC:
undetectable		 5kc0A-2ekeC:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2eke SUMO-CONJUGATING
ENZYME UBC9
(Saccharomyces
cerevisiae) 		5 / 10 ILE A  60
ILE A  45
PHE A  24
VAL A  75
ILE A 112
 None
 1.26A 5lg3F-2ekeA:
undetectable		 5lg3F-2ekeA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2eke SUMO-CONJUGATING
ENZYME UBC9
(Saccharomyces
cerevisiae) 		3 / 3 ILE A  92
VAL A  75
PRO A  73
 None
 0.70A 5uunA-2ekeA:
undetectable		 5uunA-2ekeA:
20.07