SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ekh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2ekh SH3 AND PX
DOMAIN-CONTAINING
PROTEIN 2A
(Homo
sapiens) 		5 / 12 PRO A  56
LEU A  60
VAL A  31
TYR A  17
PHE A  48
 None
 1.26A 3meeA-2ekhA:
undetectable		 3meeA-2ekhA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2ekh SH3 AND PX
DOMAIN-CONTAINING
PROTEIN 2A
(Homo
sapiens) 		5 / 12 PRO A  56
LEU A  60
VAL A  31
TYR A  17
PHE A  48
 None
 1.29A 3megA-2ekhA:
undetectable		 3megA-2ekhA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2ekh SH3 AND PX
DOMAIN-CONTAINING
PROTEIN 2A
(Homo
sapiens) 		5 / 12 VAL A  35
LYS A  38
VAL A  46
LEU A  60
THR A  13
 None
 1.14A 4yhaG-2ekhA:
undetectable		 4yhaG-2ekhA:
15.95