SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2emq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 2emq HYPOTHETICAL
CONSERVED PROTEIN
(Geobacillus
kaustophilus) 		4 / 8 PHE A 128
ILE A 109
LEU A 102
VAL A 133
 None
 0.87A 1fslB-2emqA:
undetectable		 1fslB-2emqA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 2emq HYPOTHETICAL
CONSERVED PROTEIN
(Geobacillus
kaustophilus) 		5 / 9 LEU A  17
LEU A  98
ILE A  93
GLU A 118
VAL A 115
 None
 1.45A 3tmzA-2emqA:
undetectable		 3tmzA-2emqA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2emq HYPOTHETICAL
CONSERVED PROTEIN
(Geobacillus
kaustophilus) 		5 / 9 ARG A  91
GLY A  58
LEU A  59
ASN A  90
ILE A  47
 None
 1.02A 3wdmA-2emqA:
undetectable		 3wdmA-2emqA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2emq HYPOTHETICAL
CONSERVED PROTEIN
(Geobacillus
kaustophilus) 		3 / 3 VAL A 133
GLU A 132
ILE A 109
 None
 0.60A 6f7lB-2emqA:
undetectable		 6f7lB-2emqA:
18.04